Weight Loss

A rise in the use of non-FDA-approved diabetes and obesity medications has spurred health care professionals and medical organizations to speak out about safety concerns.

SAN DIEGO — Results presented here showed patients who had significant weight loss prior to total hip arthroplasty with use of a GLP-1 receptor agonist experienced a decreased risk for complications but an increased risk for mortality.

Intentional weight loss of 5% or more, coupled with reduced waist circumference was associated with lower risk for death from cancer, CVD or any cause among postmenopausal women followed for more than 18 years, data show.

Adults with obesity and type 2 diabetes receiving once-weekly combination cagrilintide 2.4 mg and semaglutide 2.4 mg lost 15.7% of their body weight at 68 weeks, according to topline data from the REDEFINE 2 trial.

The increasingly popular obesity and diabetes drugs known as glucagon-like peptide-1 receptor agonists do not seem to worsen suicidality despite previous concerns, according to recent data published in BMJ.

Adults with type 1 diabetes have greater reductions in body weight and HbA1c after using off-label semaglutide or tirzepatide than those not using either drug, according to data published in Diabetes Technology & Therapeutics.

Published results showed patients with obesity who took anti-obesity medications and had postoperative weight loss within 1 year after total joint arthroplasty may be at significantly decreased risk for revision at 5 and 10 years.

Unintentional weight loss prior to kidney transplant evaluation may be linked to lower listing odds and higher waitlist mortality for frail patients with obesity, a study found.

Carbonated water may indirectly produce weight loss by boosting metabolism and blood glucose uptake, according to a brief report in BMJ Nutrition, Prevention & Health.

A randomized controlled trial demonstrated a significantly reduced incidence of type 2 diabetes among individuals with metabolic syndrome who received daily metformin with or without a Mediterranean diet intervention.