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Unresectable Melanoma

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Advanced Melanoma Immunotherapy Landscape: Positioning Novel and Emerging Agents

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Melanoma Insights: Focus on High-Risk Early-Stage to Advanced Disease Management

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News
July 30, 2024
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Immunotherapy combination improves response in unresectable melanoma

An immunotherapy combination improved outcomes compared with historical control for certain patients with advanced melanoma, according to a topline data announcement.

News
April 21, 2024
9 min read
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Lifileucel approval the start of a ‘glorious future’ for cell therapy in solid tumors

It took more than 35 years for tumor-infiltrating lymphocytes, which Steven A. Rosenberg, MD, PhD, and colleagues first reported on in 1988 for the treatment of advanced melanoma, to progress enough to gain FDA approval.

News
June 15, 2020
4 min read
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Fewer nivolumab doses with ipilimumab appear effective in unresectable melanoma

The first two doses of nivolumab with ipilimumab appeared to drive efficacy and toxicity of the combination among certain patients with melanoma, according to phase 2 study results presented during the ASCO20 Virtual Scientific Program.

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August 14, 2019
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Dabrafenib-trametinib combination confers durable survival benefit in BRAF-mutated metastatic melanoma

About one-third of patients with unresectable or metastatic melanoma with a BRAF V600E or BRAF V600K mutation who received first-line dabrafenib plus trametinib in two clinical trials achieved 5-year OS, according to results of a data analysis published in The New England Journal of Medicine.