University Of Washington

CHICAGO — CPX-351 appeared well-tolerated and effective followed by a chemotherapy regimen among children with relapsed or refractory acute myeloid leukemia, according to results of a phase 1/phase 2 AAML 1421 trial presented at ASCO Annual Meeting.

SAN DIEGO — Patients with Crohn’s disease who were perioperatively managed with an enhanced recovery protocol experienced a reduction in length of stay and faster recovery without an increase in adverse events, according to a study presented at Digestive Disease Week.

NEW YORK — Petros Grivas, MD, PhD, medical oncologist and clinical director of the genitourinary cancers program at University of Washington and Fred Hutchinson Cancer Research Center, presented two talks at HemOnc Today New York.

PHILADELPHIA — Depression and anxiety are common disorders seen in primary care practices, with up to 20% of patients presenting with symptoms, according to a speaker here at the ACP Internal Medicine Meeting 2019.

In 2017, a poor diet, defined as one high in sodium and low in whole grains and fruits, contributed to 11 million deaths globally, accounting for roughly one of every five deaths , according to research published in The Lancet.

NEW YORK — First-line treatment of patients with metastatic renal cell carcinoma has evolved considerably in the past 18 months with FDA approval of cabozantinib monotherapy and the combination of ipilimumab and nivolumab.

SAN FRANCISCO — The combination of pembrolizumab and olaparib demonstrated activity in men with metastatic castration-resistant prostate cancer who previously received docetaxel and no more than two second-generation hormone treatments, according to results from the phase 1b/2 KEYNOTE-365 umbrella trial presented at Genitourinary Cancers Symposium.

Acute myeloid leukemia historically has been one of the more deadly and difficult-to-treat cancers, with a 5-year survival rate below 30%.

Avelumab demonstrated antitumor activity and safety among heavily pretreated patients with recurrent or refractory ovarian cancer, according to results from the JAVELIN solid tumor study published in JAMA Oncology.

SAN DIEGO — B-cell maturation antigen chimeric antigen receptor T cells that harbor a fully human single-chain variable fragment with a defined composition of CD4-positive and CD8-positive T cells appeared potent among patients with heavily pretreated, high-risk multiple myeloma, according to study results presented at ASH Annual Meeting and Exposition.