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University Of Texas Southwestern Medical Center

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August 09, 2023
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‘Lipid paradox’ may obscure cardiovascular risk in patients with inflammatory disease

AUSTIN, Texas — Providers should carefully consider the “lipid paradox” when monitoring cardiovascular risks in patients with rheumatic inflammatory diseases, noted a presenter at the 2023 Rheumatology Nurses Society annual conference.

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July 31, 2023
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MACE, malignancy risks similar for upadacitinib, adalimumab in rheumatoid arthritis

Although major adverse cardiac events, malignancy and venous thromboembolism are more frequent in at-risk patients with rheumatoid arthritis, rates are similar between those receiving upadacitinib vs. adalimumab, according to data.

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June 26, 2023
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‘This raises the bar’: Phase 2 data show 24% weight loss with triple-agonist retatrutide

SAN DIEGO — Adults with obesity who received the highest dose of a once-weekly injection of retatrutide lost an average of 24.2% of their body weight at 48 weeks compared with placebo, data from a phase 2 study show.

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June 19, 2023
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Societies update guideline on definitive local therapy for oligometastatic NSCLC

American Society for Radiation Oncology, in collaboration with European Society for Radiotherapy and Oncology, has issued a guideline on use of definitive local therapy for patients with oligometastatic non-small cell lung cancer.

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May 30, 2023
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Lp(a) level varies widely among Hispanic US adults

Median lipoprotein(a) levels vary widely among Hispanic or Latino U.S. adults, with the highest median values seen among those self-identifying as Cuban, Dominican or Puerto Rican, researchers reported.

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May 22, 2023
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‘A ton of hurdles’ stand in the way of precision medicine for rheumatoid arthritis

The slow march toward precision medicine in rheumatoid arthritis features increased use of serum biomarkers and novel approaches to biopsy, but “a ton of hurdles” remain, according to a presenter at the Biologic Therapies Summit.

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April 26, 2023
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Polypharmacy lowers odds for initiating recommended heart failure medications

Patients prescribed a higher number of overall medications had a lower probability of initiating or achieving optimal guideline-directed medical therapy for HF, despite higher risk for long-term outcomes, data show.

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November 29, 2022
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Upadacitinib effective in patients with RA who failed prior TNF inhibitor therapy

PHILADELPHIA — Among patients with rheumatoid arthritis who had an inadequate response or intolerance to TNF inhibitors, upadacitinib demonstrated clinically meaningful and improved efficacy over 24 weeks, according to a post-hoc analysis.

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November 14, 2022
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2D, 3D MRI may accurately measure ACL foot plate anatomy before surgery

Despite small differences in anterior tibial and inter-meniscal ligament measurements, both 2D and 3D MRI may be used to delineate ACL foot plate anatomy for preoperative graft placement planning, according to published results.

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October 23, 2022
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Patients with scleroderma should receive regular pulmonary arterial hypertension screening

SAN DIEGO — Pulmonary arterial hypertension’s prevalence and rate of progression in patients with connective tissue diseases should make regular screening a priority, according to a speaker at the Congress of Clinical Rheumatology West.

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