University Of Sydney

Relatlimab plus nivolumab continued to demonstrate a PFS benefit compared with nivolumab alone for patients with previously untreated metastatic or unresectable melanoma, according to a study presented during an ASCO Plenary Series session.

Randomized clinical trials of antidepressants often contain placebo run-in periods despite their apparent lack of benefits to outcome, according to results of a systematic review and meta-analysis published in JAMA Psychiatry.

A re-analysis of thyroid imaging reporting and data system ultrasound scoring after molecular analysis is a cost-effective option to assist with preoperative diagnosis of indeterminate thyroid nodules, data from a retrospective study show.

Quarter doses of four antihypertensive medications vs. monotherapy in patients with hypertension.

Patients with psoriatic arthritis prefer oral over subcutaneous biologics, and prioritize complication avoidance and the ability to work and perform ordinary activities over clinical efficacy, according to data.

Use of a “quadpill” capsule containing quarter doses of four antihypertensive medications conferred greater BP reductions compared with monotherapy, with similar safety and tolerability, a speaker reported.

Few studies have evaluated infant and parental outcomes of false-positive results from newborn screening of congenital hypothyroidism, and most studies are low or moderate quality, according to a systematic review.

Pembrolizumab extended RFS compared with high-dose interferon or ipilimumab as adjuvant therapy for patients with high-risk melanoma, according to randomized phase 3 study results presented during the virtual ASCO Annual Meeting.

Most herbal and dietary supplements do not promote a clinically significant weight loss in adults, according to data from two systematic reviews presented at the European Congress on Obesity virtual meeting.

Two dosing regimens of tanezumab yielded comparable outcomes in pain and function as NSAIDs across a number of osteoarthritis patient subgroups, according to a speaker at the 2021 OARSI World Congress virtual meeting.