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University Of Pittsburgh

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December 16, 2019
10 min read
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Work out robotics value equation before adoption

Work out robotics value equation before adoption

Adoption of robotic systems by orthopedic surgeons has been slow and limited due to lack of improved efficiencies, the requirement of significant capital expenditure and no convincing evidence of changes in outcomes, according to an article in The Journal of Arthroplasty, by Brian S. Parsley, MD, in 2018. However, since these were first introduced in the specialty, robotics have continued to evolve, Parsley noted, which provide greater opportunities for advanced surgical planning, optimization of component placement and improved overall mechanical alignment.

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December 13, 2019
5 min read
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Residual cancer burden predicts long-term outcomes across breast cancer subtypes

Residual cancer burden predicts long-term outcomes across breast cancer subtypes

SAN ANTONIO — Residual cancer burden after neoadjuvant chemotherapy accurately predicted long-term recurrence risk and survival across all breast cancer subtypes, according to results of a meta-analysis presented at San Antonio Breast Cancer Symposium.

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December 13, 2019
4 min read
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Menopausal hormone therapy regimens have opposite lasting effects on breast cancer incidence

Menopausal hormone therapy regimens have opposite lasting effects on breast cancer incidence

SAN ANTONIO — Two common hormone therapy regimens had opposite long-term effects on breast cancer incidence among postmenopausal women, according to results from two large randomized controlled Women’s Health Initiative trials presented at San Antonio Breast Cancer Symposium.

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December 12, 2019
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Margetuximab extends survival in relapsed HER2-positive metastatic breast cancer

Margetuximab extends survival in relapsed HER2-positive metastatic breast cancer

SAN ANTONIO — Margetuximab plus chemotherapy conferred a numerically small but statistically significant PFS and OS compared with trastuzumab plus chemotherapy for patients with relapsed or refractory HER2-positive metastatic breast cancer, according to results of a second interim analysis of the randomized phase 3 SOPHIA trial presented at San Antonio Breast Cancer Symposium.

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November 08, 2019
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Anti-CD73 antibody agent appears safe, shows promise in advanced cancers

NATIONAL HARBOR, Md. — An investigational anti-CD73 antibody appeared safe and demonstrated promising antitumor activity among patients with advanced cancers, according to phase 1/1b trial data presented at Society for Immunotherapy of Cancer Annual Meeting.

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October 17, 2019
2 min read
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Study lays groundwork for understanding RA-ILD/RA-IPF overlap

Comparative serum protein biomarker profiling may allow researchers to identify patients with rheumatoid arthritis-associated interstitial lung disease and/or idiopathic pulmonary fibrosis, according to findings published in Arthritis Rheumatology.

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September 18, 2019
14 min read
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Out for Blood: Biomarkers Paving the Road to Personalized Medicine for Rheumatic Diseases

Out for Blood: Biomarkers Paving the Road to Personalized Medicine for Rheumatic Diseases

There are endless idioms about blood. It is thicker than water, but one cannot get it from a stone. Truman Capote wrote about the cold version, rock band Foreigner sang about the hot version. When it comes to rheumatic diseases, researchers are out for blood — blood-based biomarkers, that is.

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August 23, 2019
2 min read
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Hospital choice could affect pediatric mortality during emergencies

Hospital choice could affect pediatric mortality during emergencies

Findings published in Pediatrics suggest that a child’s chance of survival in an emergency may depend on the hospital where they receive care.

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August 13, 2019
2 min read
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Risk for kidney scarring spikes with two or more febrile UTIs

Risk for kidney scarring spikes with two or more febrile UTIs

Children with more than one febrile UTI are at a significantly increased risk for kidney scarring, according to findings published in JAMA Pediatrics. Researchers wrote that the risk for scarring increases with each additional febrile infection.

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July 25, 2019
2 min read
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HemOnc Today honors Next Gen Innovators

HemOnc Today held a reception at ASCO Annual Meeting to honor its third class of Next Gen Innovators.

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