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March 16, 2021
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Benefit of atezolizumab regimen may be limited to triple-negative breast cancer subset

Benefit of atezolizumab regimen may be limited to triple-negative breast cancer subset

The benefit of atezolizumab plus nab-paclitaxel in advanced triple-negative breast cancer appeared limited to patients with PD-L1 immune cell-positive tumors, an exploratory analysis of the IMpassion130 trial showed.

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March 04, 2021
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Dermatomyositis, older age increase cancer risk in idiopathic inflammatory myopathies

Dermatomyositis, older age increase cancer risk in idiopathic inflammatory myopathies

Dermatomyositis, older age and anti-transcriptional intermediary factor-1 gamma positivity are associated with a significantly increased risk for cancer in patients with idiopathic inflammatory myopathies, according to a meta-analysis.

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March 03, 2021
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Type 1 diabetes onset before menarche shortens reproductive window

Type 1 diabetes onset before menarche shortens reproductive window

Women who had type 1 diabetes onset before menarche have a reproductive period nearly 3 years shorter than women without diabetes, according to a study published in Menopause.

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March 02, 2021
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High dietary inflammatory index may be associated with low back pain

Results presented at the Association of Academic Physiatrists Annual Meeting showed that a pro-inflammatory diet may be associated with the prevalence of low back pain.

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February 22, 2021
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Hypertensive disorders of pregnancy impact heart structure, function over time

Hypertensive disorders of pregnancy impact heart structure, function over time

Women with hypertensive disorders of pregnancy or hypertension after pregnancy had significant differences in left ventricular structure and function over time, researchers reported.

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February 04, 2021
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FMT converts cancer immunotherapy non-responders to responders

FMT converts cancer immunotherapy non-responders to responders

Adding fecal microbiota transplantation to treatment in patients with programmed cell death protein 1 melanoma altered the gut microbiome and reprogrammed tumor microenvironment to overcome resistance to anti-programmed cell death protein 1 therapy, according to study results.

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January 11, 2021
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Estradiol may influence association between HDL cholesterol, aortic calcification

Estradiol may influence association between HDL cholesterol, aortic calcification

High HDL cholesterol levels alone may not be cardioprotective for midlife women; estradiol may influence the risk for cardiovascular disease, according to data from the SWAN Heart study.

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January 06, 2021
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Genetic biomarker linking Takayasu arteritis, IBD may guide targeted therapies

Genetic biomarker linking Takayasu arteritis, IBD may guide targeted therapies

When a disease has no clear etiology and no cure — as is the case with Takayasu arteritis — any advance feels like a big advance.

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December 10, 2020
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Adjuvant abemaciclib improves outcomes for certain patients with high-risk breast cancer

Adjuvant abemaciclib improves outcomes for certain patients with high-risk breast cancer

Extended follow-up of a randomized phase 3 trial presented at the virtual San Antonio Breast Cancer Symposium showed the addition of abemaciclib to endocrine therapy continued to benefit certain patients with high-risk breast cancer.

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December 04, 2020
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Menopausal transition heralds elevated CV risk; early prevention is vital

Menopausal transition heralds elevated CV risk; early prevention is vital

During the menopausal transition, women have an increased prevalence of cardiometabolic and CV risk factors; however, data on early preventive strategies are lacking, according to a new statement from the American Heart Association.

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