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University Of Michigan Ann Arbor

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March 25, 2019
16 min read
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New indications may accelerate ‘explosion’ in CAR T-cell therapy, but more education still needed

New indications may accelerate ‘explosion’ in CAR T-cell therapy, but more education still needed

Years of research into chimeric antigen receptor T-cell therapy for cancer treatment is finally paying dividends.

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March 12, 2019
3 min watch
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VIDEO: Novel patient-reported QOL tool may improve clinical trial outcomes in IBD

VIDEO: Novel patient-reported QOL tool may improve clinical trial outcomes in IBD

In this exclusive video from the Congress of the European Crohn’s and Colitis Organisation, Peter D.R. Higgins, MD, PhD, director of the IBD program at the University of Michigan, discusses a new patient-reported outcome tool that was developed and used to assess experience and quality of life in patients with ulcerative colitis.

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February 08, 2019
6 min read
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Personalized context of the cancer cell

Personalized context of the cancer cell

For decades, prognostic markers and therapeutics have been focused largely on the cancer cell’s growth patterns in tissue culture or in animal models.

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December 21, 2018
2 min read
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Benzodiazepine use among US adults higher than previously reported

Benzodiazepine use among US adults higher than previously reported

The prevalence of benzodiazepine use among adults in the United States was higher than previously reported, according to a study analyzing data from the National Survey on Drug Use and Health.

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December 20, 2018
3 min read
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Cell therapy fails to improve cardiac recovery in advanced HF

CHICAGO — Among patients with advanced HF designated for left ventricular assist device therapy, mesenchymal precursor cells did not improve cardiac recovery, but there was a signal of benefit in ischemic HF, according to the results of the LVAD MPC-II trial.

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December 05, 2018
5 min read
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FDA panel discusses study design, indications for renal denervation as hypertension treatment

FDA panel discusses study design, indications for renal denervation as hypertension treatment

An FDA advisory committee panel discussed several topics regarding the clinical evaluation of device-based therapies, including renal denervation for patients with hypertension.

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September 02, 2018
2 min read
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Prostate Cancer Foundation presents Young Investigator Awards

The Prostate Cancer Foundation granted $6 million to 29 early-career scientists through its Young Investigator Awards program.

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August 27, 2018
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CDC guidelines may be linked to greater declines in opioid prescribing

CDC guidelines may be linked to greater declines in opioid prescribing

Opioid prescriptions have steadily decreased since 2012, but after the release of the CDC’s opioid prescribing guideline in 2016, several risky prescribing practices have declined at a significantly faster rate, according to research published in Annals of Internal Medicine.

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July 28, 2018
2 min read
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American Society for Radiation Oncology members receive fellow designation

American Society for Radiation Oncology designated 35 members as ASTRO fellows.

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June 26, 2018
13 min read
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Finally, new drugs for bad bugs: What’s available and what’s in the pipeline

Finally, new drugs for bad bugs: What’s available and what’s in the pipeline

Many years ago, I worked on new and exciting antibiotics that had activity against naturally resistant organisms such as Pseudomonas and Proteus species. Some of these antibiotics were ampicillin, first-generation cephalosporins and tobramycin. We are now in a new ball game of acquired resistance, and for this report, I have turned over the job of describing some of the newer antibiotics to researchers who are in the forefront of antimicrobial resistance. – by Donald Kaye, MD, MACP

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