University Of Leeds
Worse diabetes severity increases risk for mortality after severe hypoglycemia
Diabetes Severity Score is the only factor significantly linked to greater mortality risk among older adults with type 2 diabetes experiencing severe hypoglycemia, according to study data published in Diabetes & Vascular Disease Research.
High anti-CCP, pain in hands, feet linked to increased risk for inflammatory arthritis
High anti-cyclic citrullinated peptide levels and pain in the hands or feet indicate an increased risk for progression to inflammatory arthritis, especially rheumatoid arthritis, according to data published in Arthritis Research & Therapy.
Dactylitis signals greater disease burden in early psoriatic arthritis
Dactylitis indicates a more severe disease phenotype independently linked to increased disease burden, with greater bone erosion, in early DMARD-naïve psoriatic arthritis, according to data published in the Annals of the Rheumatic Diseases.
Zanubrutinib outperforms ibrutinib in advanced CLL, small lymphocytic lymphoma
Zanubrutinib induced a superior overall response rate compared with ibrutinib among patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma, according to study results.
New wrinkle in COVID-19 care: COVID-associated vasculitis or vasculitis mimic?
Clinicians who treat vasculitides are accustomed to uncertainty. Vasculitis, in its varied forms, shares symptoms with an entire cross-section of unrelated conditions that can prompt frequent misdiagnoses and potentially fatal treatment decisions.
Guselkumab increases enthesitis resolution rates in psoriatic arthritis
Treatment with guselkumab results in higher enthesitis resolutions rates at week 24, with maintenance of those higher rates through 1 year, in patients with psoriatic arthritis, according to data published in Rheumatology.
Mortality rate in Cushing’s syndrome ‘unacceptably high’
A large study of mortality in Cushing’s syndrome calculated a threefold higher mortality rate for these patients, with cerebrovascular and atherosclerotic vascular diseases and infection accounting for 50% of deaths, researchers reported.
'Checklist' may help distinguish overlapping features of COVID-19, giant cell arteritis
Giant cell arteritis and COVID-19 both feature headache, fever, elevated C-reactive protein and cough as symptoms, whereas jaw claudication, visual loss and platelet and lymphocyte counts may be more discriminatory, according to findings.
Cardiac monitor insertion after cryptogenic stroke may be cost-effective in US
Immediate insertion of a cardiac monitor following first cryptogenic stroke was cost-effective in the U.S. compared with delayed implantation after 30-day Holter monitoring, according to a study.