University Of Leeds

Oral methotrexate in combination with usual analgesics significantly reduced knee osteoarthritis pain and stiffness, and improved function, vs. placebo, according to data published in Annals of Internal Medicine.

SAN DIEGO — A combination of targeted therapies used for a response-directed duration significantly improved outcomes compared with chemoimmunotherapy for fit patients with untreated chronic lymphocytic leukemia, according to study results.

The 2017 FDA approval of tocilizumab as the first drug to specifically treat giant cell arteritis ushered in a new era in the management of the disease, with hopes that it would eliminate the need for steroids in the condition altogether.

Treatment for anal cancer has advanced significantly over the years, but the standard radiotherapy regimen used regardless of tumor size has led to various immediate and long-term adverse events.

Although the breakthrough infection rate has been high in patients using rituximab during the later stages of the COVID-19 pandemic, a small proportion of those who are fully vaccinated develop severe outcomes, according to data.

Peter Hillmen, MD, PhD, and John Atkinson, MD, will receive the Ernest Beutler Lecture and Prize at this year’s ASH Annual Meeting & Exposition.

PHILADELPHIA — A novel therapy targeting human programmed cell death protein-1 showed efficacy in rheumatoid arthritis with an attractive safety profile, according to a speaker at ACR Convergence 2022.

In a large cohort of women, those who were vegetarians demonstrated an elevated risk for hip fracture compared with their meat-eating counterparts, according to recent research.

Patients with persistent midfoot pain, but no radiological evidence of osteoarthritis, might have under-recognized disease in the second and third cuneiform metatarsal joints, according to data published in Arthritis Care and Research.

In patients with early psoriatic arthritis who are naïve to disease-modifying antirheumatic drugs, swollen joints are a better predictor of synovitis than tender joints, according to data published in Rheumatology Advances in Practice.