University Of Cincinnati

A small percentage of children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia who received a second infusion of tisagenlecleucel had clinically meaningful responses, data from a retrospective study showed.

Direct oral anticoagulants showed greater efficacy and cost-effectiveness than low-molecular-weight heparin for treatment of cancer-associated thrombosis, according to data published in Annals of Internal Medicine.

Lower target systolic BP after successful endovascular therapy demonstrated a signal of harm and only a marginal probability of benefit toward infarct volume and disability, a speaker reported.

In patients with juvenile fibromyalgia, pain distribution throughout the body may be less important for clinical outcomes and impairment than other factors, according to data published in Arthritis Care & Research.

A driver training software program reduced the frequency of long glances from the roadway among adolescents with ADHD compared with a control training program, a randomized controlled trial found.

The benefits of gender-affirming hormone therapy outweigh the risks for transgender women of all ages as well as those with comorbidities, according to a speaker at the 2022 North American Menopause Society annual meeting.

Women with severely low breast milk production have higher BMI, blood pressure and plasma lipid levels compared with those with normal milk production, according to a study published in Breastfeeding Medicine.

CHICAGO — Combining brentuximab vedotin with a chemotherapy regimen as first-line therapy conferred an objective response in 88% of younger patients with newly diagnosed advanced-stage classical Hodgkin lymphoma, study results show.

SAN FRANCISCO — Dupilumab reduced severe exacerbations and improved prebronchodilator FEV1 in children aged 6 to 11 years with uncontrolled moderate to severe asthma with or without ongoing atopic comorbidities, according to new data.

DALLAS — Neoadjuvant pembrolizumab did not increase risk for serious surgical complications among patients with advanced oral cavity cancer, study results presented at American Head & Neck Society Annual Meeting showed.