University Of California Los Angeles

The FDA approved durvalumab in combination with standard chemotherapy as first-line treatment of adults with extensive-stage small cell lung cancer.

A 5-day regimen of neoadjuvant radiotherapy appeared as effective and safe as the conventional 5-week regimen for patients with soft tissue sarcoma, according to results of a prospective phase 2 study published in Clinical Cancer Research.

The Endocrine Society recommends medical management with a moderate level of evidence; in particular, steroidogenesis inhibitors as a second-line treatment after surgery for people with Cushing’s disease, either with or without radiotherapy, and as primary treatment for ectopic adrenocorticotropic hormone (ACTH) secretion. The guideline also recommends pituitary-directed medical treatments for patients who are not surgical candidates or who have persistent disease after surgery. The choice of medical therapy should be guided by efficacy, individual patient factors and cost.

Partial breast reirradiation without mastectomy appeared as effective as mastectomy for treatment of breast cancer recurrence in the ipsilateral breast after lumpectomy and whole breast irradiation, according to results of the phase 2 NRG Oncology/RTOG1014 trial published in JAMA Oncology.

SAN ANTONIO — Two common hormone therapy regimens had opposite long-term effects on breast cancer incidence among postmenopausal women, according to results from two large randomized controlled Women’s Health Initiative trials presented at San Antonio Breast Cancer Symposium.

The NCI awarded an $8.7 million grant to the prostate cancer program at UCLA Jonsson Comprehensive Cancer Center and UCLA Health.

The UCLA Jonsson Cancer Center has begun enrolling patients in its latest chimeric antigen receptor T-cell immunotherapy trial for patients with relapsed or refractory non-Hodgkin’s B-cell lymphoma or chronic lymphocytic leukemia.

SAN FRANCISCO — Prevymis safely resolved inflammation among patients with cytomegalovirus-associated uveitis, according to a presentation at the American Academy of Ophthalmology annual meeting.

The National Academy of Medicine announced the election of 90 regular members and 10 international members.

The Cancer Research Institute presented the William B. Coley Award to Antoni Ribas, MD, PhD.