University Of Athens

SAN DIEGO — Daratumumab monotherapy significantly delayed progression of high-risk smoldering multiple myeloma to active multiple myeloma compared with active monitoring, according to results of the randomized phase 3 AQUILA study.

SAN FRANCISCO — Atezolizumab monotherapy improved OS compared with chemotherapy among patients with PD-L1-high, cisplatin-ineligible metastatic urothelial carcinoma, according to an exploratory analysis of a randomized phase 3 study.

Patients with ANCA-associated vasculitis who have a history of autoimmune disease prior to diagnosis may have fewer relapses following remission, according to data published in Clinical and Experimental Rheumatology.

Diets with higher inflammatory potential appeared linked to increased risk for incident dementia, according to results of a population-based study published in Neurology.

Empagliflozin reduced risk for heart failure hospitalization similarly in people with and without type 2 diabetes and delayed the need for insulin initiation in those with diabetes or prediabetes, data from EMPEROR-Preserved show.

Healthy adults with the highest sensitivity to glucocorticoids have a proteomic profile suggesting a greater capability for responding to stressful stimuli compared with those with lowest sensitivity, according to study data.

People with affective disorders had the highest rates of nosocomial PTSD 3 months after discharge from psychiatric hospitalization, according to a study in Psychiatry Research.

Women with circadian rhythm misalignment may be at a greater risk for developing ovarian endometriosis, according to data presented at the European Congress of Endocrinology.

Approximately 15% of patients with mild to moderate COVID-19 have thyroid dysfunction, and SARS-CoV-2 may directly affect thyroid morphology and function, worsening preexisting autoimmune thyroid disease, data from a review show.