Uncontrolled Hypertension

An FDA advisory panel voted 10-2 that the benefits of an ultrasound renal denervation system outweigh the risk for use in adults with uncontrolled hypertension who are unresponsive or intolerant to antihypertensive medications.

NEW ORLEANS — Baxdrostat, an aldosterone synthase inhibitor, did not lower systolic BP compared with placebo at 8 weeks in patients with uncontrolled hypertension, but nonadherence may have been a factor, researchers reported.

Black women aged 20 to 50 years with hypertension are more than twice as likely to have uncontrolled BP compared with white women, independent of social determinants of health and modifiable health behaviors, researchers reported.

CHICAGO — An ultra-low-dose four-drug quad therapy may improve BP control among patients with hypertension, with no increased safety risk, compared with angiotensin receptor blocker monotherapy, according to a small, first-in-U.S. study.

Data from a global BP screening program show adults with a history of stroke were more than twice as likely to have hypertension, with one-third of those having untreated or inadequately treated BP, researchers reported.

More than half of low-income African American women with uncontrolled hypertension had symptoms of depression, according to results of a secondary analysis of a randomized clinical trial published in JAMA Psychiatry.

Patients who received an at-home BP monitor and coaching via a smartphone app to promote healthy behaviors experienced similar reductions in BP as patients who used a BP tracking app and monitor, according to research published in JAMA Network Open.