Uncontrolled Hypertension
CPAP decreases blood pressure in patients with OSA, uncontrolled hypertension
Among patients with moderate to severe obstructive sleep apnea and uncontrolled hypertension, some measures of blood pressure fell significantly with 6-month CPAP use, according to data published in Annals of the American Thoracic Society.
ACC announces lineup of 2025 Scientific Session late-breakers
The American College of Cardiology announced the late-breaking science lineup for its Scientific Session to be held March 29-31 in Chicago and online.
Most adults unaware they have uncontrolled hypertension
A significant percentage of adults in the United States are unaware they have hypertension, according to results from a cross-sectional analysis published in JAMA Network Open.
A single combination pill can improve blood pressure control, reduce polypharmacy
A polypill containing multiple blood pressure-lowering drugs may be an effective solution to addressing both uncontrolled hypertension and polypharmacy causing non-adherence to antihypertensive medications, speakers reported.
Novo Nordisk ends trial for drug to treat hypertension in patients with advanced CKD
Novo Nordisk has stopped phase 3 clinical trials for its drug ocedurenone after it failed to meet its primary endpoint for treating uncontrolled hypertension in patients with advanced chronic kidney disease, according to a company press release.
Modest, mixed BP benefits seen with alcohol-mediated renal denervation: TARGET BP-1
ATLANTA — Adults with uncontrolled and treatment-resistant hypertension saw a modest reduction in 24-hour ambulatory BP with alcohol-mediated renal nerve denervation, although other mixed findings complicate the picture, researchers reported.
FDA approves aprocitentan for treatment of hypertension in adults with uncontrolled BP
Idorsia announced that the FDA has approved aprocitentan, its antihypertensive drug, for treatment of hypertension in combination with other drugs in patients whose BP is not adequately controlled on other drugs.
Clinical decision support system may improve hypertension management in adults with CKD
A computerized clinical decision support system could improve the management of uncontrolled hypertension in adults with chronic kidney disease, according to published data.
Phase 2 trial of novel injectable antihypertensive drug meets primary endpoint
Alnylam announced that the KARDIA-2 phase 2 trial of its novel injectable antihypertensive drug zilebesiran met its primary endpoint.
Radiofrequency renal denervation cost-effective for uncontrolled hypertension
Researchers reported that radiofrequency renal denervation is estimated to be cost-effective for uncontrolled hypertension despite multiple antihypertensive medications, at 13,482 British pounds per quality-adjusted life-years gained.