Ulcerative Colitis

Among the top stories in gastroenterology last week were the FDA’s revision of draft guidance on the clinical evaluation of gastroparesis drugs and a study that found patients with Crohn’s disease are at higher risk for myocardial infarction than the general population.

Landos Biopharma has completed a $60 million Series B round.

Among the top stories in gastroenterology last week were a video interview from GI Outlook 2019 that focused on the future of colorectal cancer screening and its viability in practice management and a guest commentary that provided tips on separating fact from fiction in a recent report regarding a patient with Crohn’s disease.

The chronic intestinal inflammation common in Crohn’s disease and ulcerative colitis appeared to increase the risk for type 2 diabetes, according to a study published in Clinical Gastroenterology and Hepatology.

Results obtained through fecal immunochemical tests and levels of fecal calprotectin could help identify patients with ulcerative colitis with endoscopic markers of disease severity, according to study results.

Patients with ulcerative colitis who smoke or have never smoked experience similar outcomes in terms of therapies they use, hospitalization and surgery, according to study results.

Patients with Crohn’s disease are at higher risk for myocardial infarction than the general population, according to study results.

Recently published studies have demonstrated new developments in ulcerative colitis and Crohn’s disease.

Pediatric patients with ulcerative colitis who do not adhere to treatment with mesalamine may experience a decrease in therapeutic efficacy, leading to a need for treatment escalation, according to study results.

Among the top stories in gastroenterology last week were the FDA issuing a safety alert and approving a boxed warning for the use of Xeljanz in patients with ulcerative colitis and a study that found patients with inflammatory bowel disease are at increased risk for venous thromboembolism for up two months after discharge from the hospital.