Ulcerative Colitis

DENVER — Wearable technology, including wrist-worn smartwatches that monitor heart rate variability, may help identify and predict flares of inflammatory bowel disease, according to data presented at the Crohn’s and Colitis Congress.

Antibiotic exposure was associated with an increased and cumulative risk for inflammatory bowel disease and was highest among individuals aged 40 years and older, according to results from a Danish study published in Gut.

Ferric carboxymaltose induced a higher rate of hypophosphatemia compared with ferric derisomaltose among patients with inflammatory bowel disease-associated iron deficiency anemia, according to results published in Gut.

Topline findings from the phase 2 ARTEMIS-UC and phase 2a APOLLO-CD trials showed that PRA023, an anti-TL1A monoclonal antibody, was safe and effective for Crohn’s disease and ulcerative colitis, Prometheus Biosciences announced.

CHARLOTTE, N.C. — Guselkumab in combination with golimumab induced greater rates of clinical remission compared with monotherapy among patients with moderate to severely active ulcerative colitis.

CHARLOTTE, N.C. — Exposure to ustekinumab and vedolizumab during pregnancy did not increase maternal and fetal complications, and researchers recommend continued use in pregnant mothers with inflammatory bowel disease.

Histologically and clinically active inflammatory bowel disease increased the risk for preterm birth, especially for women with ulcerative colitis, researchers reported.

Alembic Pharmaceuticals received FDA approval of its abbreviated new drug application for mesalamine extended-release capsules indicated for maintenance of remission in ulcerative colitis, according to a manufacturer release.

In this edition, AGA speaks out on controversial NordICC data; first US patient enrolled in phase 3 trial of obefazimod; ‘unprecedented’ shift in hepatitis A outbreaks and more.

CHARLOTTE, N.C. — In a Healio video exclusive, Rahul Dalal, MD, MPH, reported ustekinumab and tofacitinib yielded similar safety and efficacy in the treatment of a small subset of adult patients with ulcerative colitis.