Ulcerative Colitis

Fatigue is a “burdensome and highly prevalent” symptom of patients with active and inactive inflammatory bowel disease and is strongly associated with depression, researchers reported in BMC Gastroenterology.

Psychological therapies provided short-term improvements in anxiety, depression, stress and quality of life in people with quiescent inflammatory bowel disease but did not improve disease activity or prevent relapse, according to analysis.

All patients with moderate to severe ulcerative colitis in the tofacitinib OCTAVE UC clinical program who underwent colectomy had prior tumor necrosis factor inhibitor failure and most had additional risk factors, according to analysis.

Concomitant use of 5-aminosalicylic acid did not affect the overall safety and efficacy of IV or subcutaneous vedolizumab in patients with inflammatory bowel disease, according to a post hoc analysis in the Journal of Crohn’s and Colitis.

Although inflammatory bowel disease is a widespread, chronic condition in the United States, it is less commonly diagnosed in Black, Asian and Hispanic Americans, according to data reported in Gastroenterology.

Patients with inflammatory bowel disease infected with SARS-CoV-2 during the first and second waves of the pandemic experienced different symptoms and outcomes, consistent with those of the general population in Italy, researchers reported.

Among patients with ulcerative colitis, delayed Stelara responders had greater inflammatory burden at baseline compared with early responders, yet similar 1-year clinical remission outcomes, researchers reported.

In two phase 3 trials, mirikizumab induced and maintained remission at a higher rate compared with placebo among patients with moderate to severely active ulcerative colitis, according to data in The New England Journal of Medicine.

When it comes to dietary management of inflammatory bowel disease, it is important to make the distinction between diet and nutrition.