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Tyrosine Kinase Inhibitor

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October 12, 2023
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Immediate release formulation of investigational MS therapy has optimal results

Immediate release formulation of investigational MS therapy has optimal results

Treatment with immediate release tablets of a non-covalent Bruton’s tyrosine kinase inhibitor for relapsing forms of multiple sclerosis met pharmacokinetic and pharmacodynamic goals, data show.

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September 08, 2023
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Early response may predict outcomes in heavily pretreated chronic myeloid leukemia

Early response may predict outcomes in heavily pretreated chronic myeloid leukemia

Early response to ponatinib appeared predictive of survival among certain patients with chronic myeloid leukemia, according to findings presented at Society of Hematologic Oncology Annual Meeting.

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July 13, 2023
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VIDEO: Trial helps inform treatment sequencing in EGFR-mutated lung cancer

VIDEO: Trial helps inform treatment sequencing in EGFR-mutated lung cancer

Healio spoke with Charu Aggarwal, MD, MPH, about data from the Keynote-789 trial presented at this year’s ASCO Annual Meeting.

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July 11, 2023
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VIDEO: Highlights in psoriasis from Maui Derm NP+PA

VIDEO: Highlights in psoriasis from Maui Derm NP+PA

In this video, George Martin, MD, discusses highlights in the treatment of psoriasis

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June 15, 2023
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Initiating treatment after molecular testing may improve outcomes for advanced NSCLC

Initiating treatment after molecular testing may improve outcomes for advanced NSCLC

CHICAGO — Patients diagnosed with stage IV non-small cell lung cancer who received a tyrosine kinase inhibitor following clinical molecular testing had better OS, according to research presented at ASCO Annual Meeting.

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May 19, 2023
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Oral Bruton’s tyrosine kinase inhibitor reduced brain lesions in phase 2 MS trial

Oral Bruton’s tyrosine kinase inhibitor reduced brain lesions in phase 2 MS trial

Genentech announced positive results from its global phase 2 study evaluating the investigational oral Bruton’s tyrosine kinase inhibitor fenebrutinib in adults with relapsing forms of MS.

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April 25, 2023
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VIDEO: Novel tyrosine kinase 2 inhibitor ‘potentially’ effective in psoriasis treatment

VIDEO: Novel tyrosine kinase 2 inhibitor ‘potentially’ effective in psoriasis treatment

In this Healio video exclusive, Jashin J. Wu, MD, FAAD, covers a presentation from the American Academy of Dermatology Annual Meeting on TAK-279, a tyrosine kinase 2 inhibitor, in the treatment of individuals with severe psoriasis.

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February 01, 2023
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VIDEO: Treatments in the pipeline for DME

VIDEO: Treatments in the pipeline for DME

Healio spoke with Rishi P. Singh, MD, about treatments in the pipeline for diabetic macular edema.

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August 18, 2022
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TYK2 inhibitors may offer pathway for more comprehensive inflammation therapy

TYK2 inhibitors may offer pathway for more comprehensive inflammation therapy

The emergence of drugs inhibiting the JAK-STAT pathway has culminated in tyrosine kinase 2 inhibitors targeting psoriatic arthritis, lupus and other indications, noted a presenter at the 2022 Association of Women in Rheumatology conference.

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July 06, 2022
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Remibrutinib reduces rescue medication use among adults with chronic spontaneous urticaria

Remibrutinib reduces rescue medication use among adults with chronic spontaneous urticaria

Remibrutinib reduced the need for rescue medication and improved symptoms among patients with chronic spontaneous urticaria, according to a study presented at the European Academy of Allergy and Clinical Immunology Hybrid Congress.

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