Type 2 Diabetes

Middle-aged adults with type 2 diabetes have a disproportionate risk increase for COVID-19 mortality and should receive priority for early vaccination, according to a research letter published in Diabetologia.

Adding liraglutide and lifestyle counseling to duodenal mucosal resurfacing eliminated the need for insulin therapy in most patients with type 2 diabetes through 18 months, according to data from a feasibility study.

Women with type 2 diabetes and those who used metformin did not demonstrate an overall increased risk for breast cancer, according to an analysis of the Sister Study published in Annals of Oncology.

Patients with diabetes who consistently followed a low-carbohydrate diet for 6 months achieved a higher rate of remission — 32% — compared with mostly low-fat diets, according to a systematic review and meta-analysis.

Men with excess weight or type 2 diabetes may reap more pronounced metabolic benefits from exercise when training is performed in the afternoon vs. morning, according to findings from a small, retrospective study.

CV outcomes of sotagliflozin (Sanofi/Lexicon), an SGLT1/SGLT2 inhibitor, in patients with type 2 diabetes and worsening HF or high CV risk.

A healthy diet may be linked with gut microbes correlate with a lower risk developing conditions including obesity, type 2 diabetes and cardiovascular disease, according to a report published in Nature Medicine.

For patients with type 2 diabetes, SGLT2 inhibitors conferred a lower risk of developing AKI than use of GLP-1 receptor agonists or dipeptidyl peptidase-4 inhibitors, according to a network meta-analysis of clinical trials.

Approximately 10% to 17% of patients with type 2 diabetes and newly identified chronic kidney disease had their condition worsen within 2 years, according to a study published in the Clinical Kidney Journal.

Testosterone therapy with intramuscular testosterone undecanoate did not result in any adverse cardiovascular or prostate events in a cohort of men with obesity, type 2 diabetes and functional hypogonadism, clinical trial data showed.