Type 2 Diabetes

CHICAGO — The dual SGLT inhibitor sotagliflozin reduced 30- and 90-day rates of CV mortality and HF-related events when administered before hospital discharge after an episode of worsening HF, according to new data from the SOLOIST trial.

Chronic exposure to outdoor artificial light at night was associated with increased glucose levels, HbA1c and insulin resistance, according to study findings published in Diabetologia.

Sarcopenic obesity may increase the risk for chronic kidney disease among adults with type 2 diabetes, but low muscle mass without obesity was not associated with CKD, according to study results published in Obesity.

Children, adolescents and young adults with Down syndrome have higher incidence rates of type 1 and type 2 diabetes compared with matched controls without Down syndrome, according to a study published in Diabetes Care.

ORLANDO — Isuzinaxib, a pan-NOX inhibitor modulating oxidative stress by Aptabio significantly reduced urine albumin-to-creatinine ratio in patients with type 2 diabetes and chronic kidney disease, according to data at ASN Kidney Week.

CHICAGO — In the PROMINENT trial, pemafibrate lowered triglycerides but did not cut the incidence of CV events compared with placebo in patients with type 2 diabetes and mixed dyslipidemia.

SAN DIEGO — A weekly glucagon/GLP-1 dual receptor agonist conferred greater weight loss than 1 mg semaglutide at 16 weeks among adults with type 2 diabetes, according to findings from a phase 2 trial.

SAN DIEGO — A virtual diabetes-tailored weight management program resulted in beneficial and clinically meaningful effects on glucose levels, body weight and diabetes distress among adults with type 2 diabetes.

Mind- and body-based practices, including mindfulness-based stress reduction, qigong and yoga, are associated with a reduction in HbA1c for adults with type 2 diabetes, according to findings from a systematic review and meta-analysis.

Healio has launched a new point-of-care tool with modules on medical conditions to help clinicians treat patients using reliable information.