Type 2 Diabetes

WASHINGTON — Glucagon-like peptide-1 receptor agonists were associated with lower risk for progression to cirrhosis and hepatocellular carcinoma in patients with metabolic dysfunction-associated steatotic liver disease and type 2 diabetes.

A once-weekly basal insulin conferred noninferior reductions in HbA1c among insulin-naive adults with type 2 diabetes and those who receive multiple daily insulin injections, according to top-line results from two phase 3 trials.

Women reporting irregular menstrual cycles with or without diagnosed polycystic ovary syndrome are more likely to have cardiometabolic conditions such as diabetes and hypertension, according to new data from the Apple Women’s Health Study.

BOSTON — Life’s Essential 8, a campaign led by the American Heart Association, is an assortment of interventions “we can all follow” and “associated with much better outcomes,” Clyde W. Yancy, MD, MSc, MACP, MACC, FAHA, FHFSA, said.

Risk for incident fracture is higher for children born to mothers with type 2 diabetes or gestational diabetes compare with those whose mothers did not have diabetes, according to data published in the Journal of Bone and Mineral Research.

BOSTON — New recommendations from ACP on type 2 diabetes treatment include adding a GLP-1 agonist or SGLT-2 inhibitor to therapy for patients who have inadequate glycemic control, the organization announced.

ATLANTA — Adults with obesity, HF with preserved ejection fraction and type 2 diabetes saw marked improvements in HF symptoms and physical function with semaglutide 2.4 mg compared with placebo, despite less than typical weight loss.

Intensive lifestyle intervention did not significantly change eGFR slope during 10 years in patients with type 2 diabetes and preserved kidney function, researchers found in a study.

Neighborhoods that were historically redlined on Home Owners’ Loan Corporation maps in the 1930s are associated with higher diabetes prevalence than non-redlined areas after adjusting for 2010 population figures, according to study data.