Type 1 Diabetes

Approximately 34.1 million U.S. adults — more than 1 in 10 —have type 1 or type 2 diabetes, and 7.3 million of those adults who met laboratory criteria were unaware or did not report having the disease, according to data from the CDC’s 2020 National Diabetes Statistics Report.

Thyroid dysfunction is common among people with diabetes regardless of type, suggesting that biochemical thyroid screening should be a part of routine management for those with type 1 and type 2, according to an analysis of a community-based study published in Clinical Endocrinology.

An investigational, once-daily pill added to optimized insulin therapy was shown to reduce HbA1c among adults with type 1 diabetes during a 12-week trial when compared with placebo plus insulin, according to a press release from vTv Therapeutics.

Adults with type 1 diabetes who have diabetic peripheral neuropathy are more likely to experience severe hypoglycemia or diabetic ketoacidosis than their peers without peripheral neuropathy, according to findings published in Diabetes Care.

A follow-on therapy to insulin aspart was shown to be safe and effective for pump use among adults with type 1 diabetes, with no increased incidence of unexplained hypoglycemia when compared with the reference product, according to findings from an open-label crossover study published in Diabetes Technology & Therapeutics.

Financial incentive programs to support diabetes self-management in families with adolescents with type 1 diabetes may improve health outcomes, according to a qualitative study published in Pediatric Diabetes.

Intensive glucose management can help adults with type 1 diabetes avoid an initial or subsequent cardiovascular disease or major adverse cardiovascular disease event, according to findings published in Diabetes Care.

A cohort of children and adolescents with type 1 diabetes had markers of bone formation and bone resorption that were significantly decreased compared with children without diabetes, independent of diabetes duration and Tanner stages, according to findings published in Pediatric Diabetes.

Presymptomatic type 1 diabetes increases the risk for developing clinical type 1 diabetes in children aged 2 to 5 years, but can be identified via islet autoantibody screening, according to findings published in JAMA.

Adults with type 1 diabetes may be able to maintain their glucose levels in target range longer, particularly during the day, by using an artificial pancreas with rapid-acting insulin and pramlintide, according to findings published in Diabetes Care.