Transient Ischemic Attack

In patients with atrial fibrillation who had ACS or PCI, among those with prior stroke, transient ischemic attack or thromboembolism, those assigned a dual antithrombotic strategy of apixaban and a P2Y12 inhibitor had better outcomes than those assigned a vitamin K antagonist-based regimen, according to new data from the AUGUSTUS trial.

An intensified support program in addition to conventional care for patients with transient ischemic attack or minor stroke was more successful in achieving secondary prevention targets than conventional care alone.

Nonmydriatic fundus photography after suspected minor stroke or transient ischemic attack was able to differentiate between actual stroke and mimics, according to findings from the FOTO-ED TIA study presented at the International Stroke Conference.

During the 5 years after a stroke, targeting LDL of less than 70 mg/dL prevented more than one-quarter of major CV events, recurrent cerebral infarction or urgent carotid revascularization and recurrent cerebral infarction or hemorrhage vs. an LDL target of less than approximately 100 mg/dL.

AstraZeneca announced that in the phase 3 THALES study, in patients with minor acute ischemic stroke or high-risk transient ischemic attack, twice daily ticagrelor 90 mg plus aspirin met the primary endpoint of reduced risk for stroke and death at 30 days compared with aspirin alone.

ATLANTA — The incidence of cardiovascular events related to systemic lupus erythematosus peaks at 1 to 2 years following diagnosis, with an 18-fold higher risk among black patients with SLE compared with white patients, according to a speaker at the 2019 ACR/ARP Annual Meeting.

Patients with familial hypercholesterolemia who were treated in U.S. specialty clinics had a harder time achieving LDL less than 100 mg/dL than those who had atherosclerotic CVD at the start of lipid-lowering therapy.

SAN FRANCISCO — In a CT substudy of the PARTNER 3 trial of low surgical risk patients who underwent transcatheter or surgical aortic valve replacement, hypoattenuated leaflet thrombosis and reduced leaflet motion were not associated with death, MI and stroke, according to data presented at TCT 2019.