Tramadol

Results showed patients who received tramadol prior to total shoulder arthroplasty had decreased risk for complications, resource utilization, infection and revision compared with patients who received traditional preoperative opioids.

Diabetic peripheral neuropathy is a debilitating, progressive neurologic disorder that affects about 30% of adults with diabetes. Spinal cord stimulation is a newer option for addressing moderate to severe pain related to the condition.

Patients who receive tramadol for osteoarthritis demonstrate an increased risk for hip fractures, venous thromboembolism and mortality, compared with those treated with NSAIDs, according to data published in Arthritis Research and Therapy.

A daily 300 mg dose of tramadol — but not 100 or 200 mg doses — surpassed placebo in improving pain and function related to hip or knee osteoarthritis, but was linked to increasing adverse events, researchers noted in Arthritis Care & Research.

Avenue Therapeutics announced the FDA has issued a second complete response letter regarding the new drug application for intravenous tramadol as an analgesic treatment for patients with acute pain.

Opioid-associated ototoxicity, or hearing loss, appears to be an adverse event that can occur with the use of a variety of opioids, according to research published in the Journal of Medical Toxicology.

The analgesic medication tramadol was associated with a higher risk for hip fracture compared with codeine and commonly used NSAIDs, according to findings from a population-based study.

University of Texas Health Science Center at Houston implemented an opioid-minimizing, multimodal pain regimen to maximize pain relief and decrease patient exposure to opioids.

The rate of postoperative opioid prescriptions filled was seven times higher in the United States and Canada than in Sweden, according to a study recently published in JAMA Network Open.