Thyroid Cancer

MADRID — Selpercatinib improved outcomes compared with cabozantinib or vandetanib for treatment of RET-mutant medullary thyroid cancer, according to randomized phase 3 study results presented at ESMO Congress.

Men and women who developed thyroid cancer after the Chernobyl nuclear disaster had a significantly higher incidence of secondary solid tumors, according to study results published in JAMA Network Open.

Adults with low-risk thyroid cancer cite concerns about adverse outcomes, psychological distress and a negative response to their diagnosis as reasons they opted for surgery over active surveillance, according to study findings.

Adults who undergo thyroid cancer surgery at clinics performing five or fewer operations per year are more likely to have recurrence or persistent disease than those attending higher-volume centers, according to study data.

Selpercatinib extended PFS compared with two approved multikinase inhibitors for treatment of RET-mutant medullary thyroid cancer, according to the agent’s manufacturer.

Multifocal disease is not linked to a greater risk of recurrence or mortality for children and adolescents with papillary thyroid carcinoma, according to a study published in The Journal of Clinical Endocrinology & Metabolism.

Adults with postoperative hypoparathyroidism after thyroid cancer are less likely to sustain a fracture compared with those with preserved parathyroid function, according to findings published in the Journal of Bone and Mineral Research.

Levothyroxine therapy may help decrease tumor growth for adults with papillary thyroid microcarcinoma who are undergoing active surveillance, according to a study published in Thyroid.

In a small group of adults diagnosed with medullary thyroid microcarcinoma, few had disease recurrence or died during more than 6 years of follow-up, according to findings from an Australian database.

Hispanic and Asian adults diagnosed with thyroid cancer are more likely to have advanced disease, but also have better survival outcomes, compared with white adults, according to study data.