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Thyroid Cancer

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February 25, 2021
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FDA grants breakthrough therapy designation to Cabometyx for thyroid cancer subset

FDA grants breakthrough therapy designation to Cabometyx for thyroid cancer subset

The FDA granted breakthrough therapy designation to cabozantinib for treatment of certain patients with thyroid cancer, according to the agent’s manufacturer.

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February 25, 2021
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‘Overdiagnosis’ driving increased thyroid cancer incidence in children

‘Overdiagnosis’ driving increased thyroid cancer incidence in children

Thyroid cancer incidence and mortality patterns among children and adolescents worldwide mirror data for adults, suggesting overdiagnosis and a need to “explicitly recommend” against screening for the disease in asymptomatic children.

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January 20, 2021
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Thyroid disorders before, during pregnancy raise thyroid cancer risk in children

Thyroid disorders before, during pregnancy raise thyroid cancer risk in children

Children born to mothers diagnosed with thyroid disorders before or during pregnancy were significantly more likely to develop thyroid cancer, with risk persisting into adulthood, according to an analysis of registry data.

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December 01, 2020
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FDA approves Gavreto for RET-altered thyroid cancers

FDA approves Gavreto for <i>RET</i>-altered thyroid cancers

The FDA granted accelerated approval to pralsetinib for treatment of certain patients with RET-altered thyroid cancer.

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August 12, 2020
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Study data support higher-dose lenvatinib for radioactive iodine-refractory thyroid cancer

Study data support higher-dose lenvatinib for radioactive iodine-refractory thyroid cancer

An 18 mg starting dose of the oral tyrosine kinase inhibitor lenvatinib did not meet the noninferiority requirement compared with the approved, 24 mg starting dose for adults with radioactive iodine-refractory thyroid cancer, data show.

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June 11, 2020
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Lenvatinib monotherapy fails to improve survival in anaplastic thyroid cancer

Lenvatinib monotherapy fails to improve survival in anaplastic thyroid cancer

Adults with anaplastic thyroid cancer who received lenvatinib monotherapy experienced some tumor shrinkage but were not considered responders to treatment, suggesting combination therapy should be investigated, researchers reported.

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May 18, 2020
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'Pressing need' for quality data on treatment options for low-risk thyroid cancers

'Pressing need' for quality data on treatment options for low-risk thyroid cancers

Models projecting incidence of low-risk papillary thyroid cancers suggest there will be more than 200,000 new thyroid cancer diagnoses during the next 5 years, with at least 67,000 of those cases qualifying as candidates for active surveillance due to small tumor size, according to findings published in JAMA Otolaryngology Head & Neck Surgery.

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May 08, 2020
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'Consistent increase' observed in larger, more aggressive thyroid tumors in California

'Consistent increase' observed in larger, more aggressive thyroid tumors in California

A retrospective analysis of diagnosed thyroid cancer cases in California revealed a consistent increase in the diagnosis of larger and more aggressive thyroid tumors that correlated with a rise in incidence-based mortality among men and individuals with tumors larger than 1 cm, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

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April 21, 2020
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Risk for thyroid tumor growth declines with advancing age

Risk for thyroid tumor growth declines with advancing age

Advancing age may be associated with reduced risk for papillary thyroid tumor growth under active surveillance, according to findings published in JAMA Otolaryngology Head & Neck Surgery.

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April 20, 2020
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High thyroid cancer rate among 9/11 responders likely due to heightened surveillance

High thyroid cancer rate among 9/11 responders likely due to heightened surveillance

An increased rate of thyroid cancers observed among firefighters who responded to the 9/11 World Trade Center attack may be associated with heightened surveillance rather than an increase in disease, according to findings published in JAMA Internal Medicine.

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