Testosterone

Prior testosterone exposure did not impact oocyte cryopreservation outcomes among transgender and gender-diverse adolescents and young adults, according to a research letter published in Obstetrics & Gynecology.

BOSTON — In a phase 2b trial, a hormonal contraceptive gel for use by men worked faster than expected, suppressing sperm count to effective levels by week 8 of use, making it an “attractive” product, according to a speaker at ENDO 2024.

BOSTON — Most nonbinary people who initiated low-dose transdermal testosterone for gender affirmation continued taking doses that were lower than current guideline recommendations at 1 year, researchers reported at ENDO 2024.

Men with low testosterone concentrations had a higher risk for all-cause mortality, and those with very low testosterone also had an increased risk for CVD mortality, a study in Annals of Internal Medicine showed.

One-third of transgender and gender-diverse individuals on testosterone will experience at least one breakthrough bleeding episode, even after their first year of use, researchers reported in the American Journal of Obstetrics and Gynecology.

The risk for developing chronic kidney disease or cardiovascular disease is much lower among adults who achieve type 2 diabetes remission compared with those who do not, according to a post hoc analysis of the Look AHEAD trial.

Testosterone level does not influence sleep quality or sleep duration among older men, according to findings published in BMC Geriatrics.

Testosterone use among transgender men and gender-diverse people was linked to higher interest in sexual activity and also pain or discomfort during sexual activity, researchers reported.

During the past two decades, testosterone levels in American men have rapidly declined.

PoinT