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Tamoxifen

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December 08, 2021
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Tamoxifen-induced PI3 kinase pathway activation may increase uterine cancer risk

Patients with breast cancer who developed tamoxifen-associated uterine cancer had fewer phosphatidylinositol 3-kinase pathway mutations than those with de novo cases, according to results presented at San Antonio Breast Cancer Symposium.

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October 12, 2021
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Sexual dysfunction due to breast cancer care improves with nonhormonal treatments

Safe and effective treatments are available for women who experience sexual dysfunction because of breast cancer care, according to a presentation during the NAMS Annual Meeting.

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October 06, 2021
5 min read
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Medications deemed essential to breast cancer prevention

Medication can play an essential role in breast cancer prevention, Holly J. Pederson, MD, director of medical breast services at the Cleveland Clinic, said during the NAMS Annual Meeting.

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December 17, 2020
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VIDEO: Expert discusses positives, negatives from virtual SABCS meeting, RxPonder data

The virtual format of this year’s San Antonio Breast Cancer Symposium had its negatives, like missing discussions with colleagues, and its positives, according to Elias Obeid, MD, MPH.

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December 17, 2020
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VIDEO: ‘Real world’ data for patients with HER2-positive, BRCA1/2 breast cancer

In this video, Elias Obeid, MD, MPH, discussed treatment patterns and clinical outcomes of patients with germline BRCA1/2-mutated, HER2-positive advanced breast cancer.

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December 14, 2020
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VIDEO: Preventing invasive, recurrent breast cancer in postmenopausal patients

In this video, Halle Moore, MD, discussed preventive breast cancer treatments for patients who are postmenopausal and have locally excised ductal carcinoma in-situ.

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February 06, 2020
4 min read
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CYP2D6 genotype linked to tamoxifen discontinuation and prognosis, not efficacy, in breast cancer

Increasing tamoxifen dosage did not lead to a higher rate of 6-month PFS among patients with hormone receptor-positive metastatic breast cancer who have CYP2D6-variant alleles, according to results of a randomized phase 2 study.

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September 27, 2019
2 min read
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Rheumatologist input absent in disputed hydroxychloroquine guidelines

SAN DIEGO — The 2016 recommendations by the American Academy of Ophthalmology on “proper” dosage of hydroxychloroquine lacked essential input from rheumatologists who rely on the drug to improve survival in patients with systemic lupus erythematosus, according to a presentation at the 2019 Congress of Clinical Rheumatology West.

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