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December 20, 2022
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VIDEO: CAR T-cell access lags for those with relapsed refractory multiple myeloma

VIDEO: CAR T-cell access lags for those with relapsed refractory multiple myeloma

NEW ORLEANS — In this video, Samer Al Hadidi, MD, MS, FACP, discusses an analysis of access to chimeric antigen receptor T-cell therapy presented at the ASH Annual Meeting and Exposition.

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November 30, 2022
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CATCR-T cell therapy may aid in antiphospholipid syndrome through selective B-cell depletion

CATCR-T cell therapy may aid in antiphospholipid syndrome through selective B-cell depletion

PHILADELPHIA — Upcoming T-cell therapies may treat antiphospholipid syndrome and other autoimmune diseases without compromising a patient’s defenses against infection, according to data presented at ACR Convergence 2022.

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November 01, 2022
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FDA grants fast track designation to CAR monocyte therapy for peripheral T-cell lymphoma

FDA grants fast track designation to CAR monocyte therapy for peripheral T-cell lymphoma

The FDA granted fast track designation to MT-101, an investigational chimeric antigen receptor monocyte, for the treatment of relapsed or refractory peripheral T-cell lymphoma.

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October 19, 2022
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CAR T-cell therapy-related neurotoxicity linked to low blood phosphate levels

CAR T-cell therapy-related neurotoxicity linked to low blood phosphate levels

Researchers have discovered a link between neurotoxicity related to chimeric antigen receptor T-cell therapy and development of subsequent hypophosphatemia.

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October 14, 2022
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FDA grants RMAT designation to CRISPR-edited CAR-T for cutaneous T-cell lymphomas

FDA grants RMAT designation to CRISPR-edited CAR-T for cutaneous T-cell lymphomas

The FDA granted regenerative medicine advanced therapy designation to CTX130, a chimeric antigen receptor T-cell therapy under development for the treatment of mycosis fungoides and Sézary syndrome.

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June 30, 2022
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VIDEO: T-cell redirecting therapies maintain big hold in multiple myeloma space

VIDEO: T-cell redirecting therapies maintain big hold in multiple myeloma space

In this video, Amrita Krishnan, MD, director of the Judy and Bernard Briskin Center for Multiple Myeloma Research at City of Hope Cancer Center, discusses major developments in multiple myeloma presented at ASCO Annual Meeting.

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June 13, 2022
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VIDEO: T-cell lymphomas manifest differently

VIDEO: T-cell lymphomas manifest differently

CLEVELAND — Cutaneous T-cell lymphomas can often have different manifestations in the skin, according to Kevin D. Cooper, MD, chair of dermatology at Case Western Reserve University School of Medicine.

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October 21, 2021
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Children with MIS-C mount normal T-cell response to SARS-CoV-2, study finds

Children with MIS-C mount normal T-cell response to SARS-CoV-2, study finds

Children with an inflammatory syndrome linked to SARS-CoV-2 infection mount a normal T-cell response to the virus, according results from a multi-institutional study ­­reported in the European Journal of Immunology.

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October 04, 2021
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Study evaluates T-cell testing for Lyme disease

Study evaluates T-cell testing for Lyme disease

T-cell testing was nearly twice as sensitive at identifying early Lyme disease compared with the standard two-tiered serologic testing and more than three times more sensitive in the first 4 days, researchers reported at IDWeek.

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December 10, 2020
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VIDEO: CAR T-cell construct will improve efficacy for CD58 loss, mutation

VIDEO: CAR T-cell construct will improve efficacy for CD58 loss, mutation

Researchers successfully created a CAR T-cell construct to signal CD58 mutation or loss in patients with large B cell lymphomas, according to a presentation from the ASH Annual Meeting and Exposition.

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