Symptomatic Intracranial Hemorrhage

For patients with cervical artery dissection initially treated with anticoagulation, switching to antiplatelet therapy at 30 days may prevent bleeding events later, as stroke risk was lower by then, researchers reported.

Reteplase administered early after stroke symptom onset was superior vs. alteplase for improving 90-day disability, a speaker reported.

Tenecteplase IV therapy for individuals who suffered ischemic stroke was nonsuperior to placebo, according to research in the New England Journal of Medicine.

In a phase 2 trial, reteplase was well tolerated with a similar efficacy and safety profile to that of alteplase as an alternative IV thrombolytic treatment for acute ischemic stroke, researchers reported.

High maximum systolic BP in the immediate hours following endovascular therapy for ischemic stroke is associated with poor functional outcome and increased risk for symptomatic intracranial hemorrhage, according to data published in Stroke.

During endovascular therapy for large vessel occlusion stroke, more than three attempts at clot retrieval was associated with elevated risk for symptomatic intracranial hemorrhage, regardless of procedure time, researchers reported.