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Stem Cell Transplantation

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March 24, 2025
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Novel regimen reduces chronic GVHD after allogeneic stem cell transplantation

Novel regimen reduces chronic GVHD after allogeneic stem cell transplantation

A novel regimen significantly reduced risk for moderate to severe chronic graft-versus-host disease for certain patients who underwent allogeneic hematopoietic stem cell transplantation, according to randomized phase 2 study results.

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February 14, 2025
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Study links beta blocker use to mortality after stem cell transplantation

Study links beta blocker use to mortality after stem cell transplantation

Taking prescribed beta blockers during hematopoietic stem cell transplantation may increase mortality risk due to suppression of signals from nerves that promote bone marrow regeneration, according to study results.

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January 08, 2025
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Clearance of driver mutations after HSCT predicts myelofibrosis relapse, survival

Clearance of driver mutations after HSCT predicts myelofibrosis relapse, survival

Patients with myelofibrosis who cleared driver mutations within 30 days after hematopoietic stem cell transplantation survived longer and exhibited reduce risk for relapse, according to study results.

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November 18, 2024
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Stem cell transplantation does not increase risk for clonal hematopoiesis

Stem cell transplantation does not increase risk for clonal hematopoiesis

Clonal hematopoiesis did not occur significantly more often among patients who received hematopoietic stem cell transplantation than their donors, according to findings of a correlative laboratory study.

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July 18, 2024
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Q&A: Seventh case of potential HIV cure comes with a twist

Q&A: Seventh case of potential HIV cure comes with a twist

A seventh person has potentially been cured of HIV after receiving a stem cell transplant to treat blood cancer, researchers announced on the eve of the 25th International AIDS Conference.

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July 01, 2024
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VIDEO: Targeted strategies, other future research in myeloproliferative neoplasms

VIDEO: Targeted strategies, other future research in myeloproliferative neoplasms

In this video, Tania Jain, MBBS, director of the Immune Effector Cell Therapy Program and associate professor of oncology at Johns Hopkins University, discusses what she would like to see in the future of myleoproliferate neoplasms care and management.

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June 06, 2024
5 min read
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Amid suffering, a lesson learned: ‘We can always find space to hope’

Amid suffering, a lesson learned: ‘We can always find space to hope’

Editor’s note: This is the first in a series of five stories from ASCO Voices, a session during the 2024 ASCO Annual Meeting focused on the human side of oncology.

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June 05, 2024
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New approach ‘redefining what is a suitable donor’ for stem cell transplant

New approach ‘redefining what is a suitable donor’ for stem cell transplant

CHICAGO — Interim results from a phase 2 study showed positive survival outcomes for individuals who underwent peripheral blood stem cell transplantation for hematologic malignancies.

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May 10, 2024
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'The cure is in front of you': The case for stem cell transplants in systemic sclerosis

'The cure is in front of you': The case for stem cell transplants in systemic sclerosis

DESTIN, Fla. — Stem cell transplantation, accompanied by total body radiation, is the only “cure” for progressive systemic sclerosis currently available, according to a speaker at the Congress of Clinical Rheumatology East annual meeting.

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March 05, 2024
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‘Off-the-shelf’ cell therapy shows ‘very encouraging’ results for B-cell malignancies

‘Off-the-shelf’ cell therapy shows ‘very encouraging’ results for B-cell malignancies

Nearly one-half of adults with relapsed or refractory CD19-positive B-cell malignancies responded to treatment with a novel cord blood-derived natural killer cell therapy expressing a chimeric antigen receptor, study results showed.

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