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June 17, 2019
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Patients with sucrase-isomaltase deficiency less likely to respond to low-FODMAP diet for IBS-D
SAN DIEGO — Roughly half of patients who go on a low-FODMAP diet to treat diarrhea predominant irritable bowel syndrome do not respond to the change in diet. According to data presented at Digestive Disease Week, many of those patients could have a genetic variant that causes a deficiency of the sucrase-isomaltase enzyme.