St Jude Childrens Research Hospital
Risk-adapted approach may help some children with medulloblastoma avoid radiation, chemotherapy
Molecular subtyping may help develop a risk-adapted approach for treating children with medulloblastoma.
Childhood cancer survivors show lack of concern over future health
Thirty-one percent of adult survivors of childhood cancer reported a lack of concern for future health and 40% reported a lack of concern regarding risk for future cancer, according to study findings.
Maintenance chemotherapy improves OS in rhabdomyosarcoma
Analysis emphasizes need for development of pediatric cancer-specific precision therapies
Researchers at St. Jude Children’s Research Hospital determined the genomic alterations that lead to cancer among children vary from those observed among adults.
Boston Children’s Hospital named best pediatric hospital by U.S. News & World Report
VIDEO: Late health problems becoming less common in childhood cancer survivors
CHICAGO — Efforts to modify treatments in an attempt to preserve high cure rates while reducing potential late effects have translated to improved health outcomes for childhood cancer survivors, Todd M. Gibson, PhD, assistant member at St. Jude Children’s Research Hospital, said at the ASCO Annual Meeting.
Childhood cancer survivors experience fewer severe health problems
CHICAGO — Treatment modifications that extended survival for childhood cancer survivors during the past several decades also reduced incidence of serious chronic disease in these individuals later in life, according to study results presented at the ASCO Annual Meeting.
Genetic predisposition for subsequent neoplasms common in pediatric cancer survivors
Twelve percent of childhood cancer survivors harbored mutations that significantly increased their risk for developing subsequent neoplasms, according to a study presented at the American Association of Cancer Research Annual Meeting.
Philadelphia chromosome–like subtype accounts for more than 20% of adult ALL cases
Philadelphia chromosome–like acute lymphoblastic leukemia appears to be a highly prevalent ALL subtype and is associated with inferior 5-year EFS, according to a study published in Journal of Clinical Oncology.
IKZF1 genetic variants may predispose children to ALL
SAN DIEGO — Researchers have identified IKZF1 as a new pediatric acute lymphoblastic leukemia predisposition gene, according to study results presented during the late-breaking abstract session of the ASH Annual Meeting and Exposition.