St Jude Childrens Research Hospital

Molecular profiling of solid tumors in children and young adults has a significant impact on diagnosis and treatment recommendations, according to results of an interim analysis presented during the virtual ASCO Annual Meeting.

The replacement of vincristine with brentuximab vedotin in standard front-line treatment appeared safe and effective among children and adolescents with high-risk classical Hodgkin lymphoma, according to phase 2 study results.

Overweight and obesity appeared significantly associated with neurocognitive impairment during long-term follow-up of individuals who received chemotherapy for childhood acute lymphoblastic leukemia, according to a study published in Cancer.

Clara A. Mason, MSN, RNC, FNP, was a trailblazer in the advanced practice oncology nursing field.

Although Hodgkin lymphoma is a highly curable form of pediatric cancer, treatment often results in life-threatening or debilitating long-term adverse effects.

Adults who received radiation therapy during childhood for abdominal and pelvic cancers appeared more likely than the general population to experience body composition abnormalities and worse cardiometabolic outcomes, study results showed.

Severe hearing loss among survivors of childhood cancer appeared associated with neurocognitive deficits independent of the neurotoxic therapy they received, according to results of a cross-sectional study published in JAMA Oncology.

Pediatric cancer survivors who harbor pathogenic variants in DNA repair genes have an increased risk for subsequent neoplasms, according to study results published in Journal of Clinical Oncology.

James R. Downing, MD, received the inaugural AACR-St. Baldrick’s Foundation Award for Outstanding Achievement in Pediatric Cancer Research.

Certain long-term childhood cancer survivors appeared more likely than their siblings who never had cancer to experience pain as adults, according to a report of the Childhood Cancer Survivor Study published in Cancer.