Squamous Cell Carcinoma

by Brook Brouha, MD, PhD

Rates of squamous cell carcinoma of the anus and related mortality have risen sharply over the past 15 years, according to results of a retrospective study published in Journal of the National Cancer Institute.

Tipifarnib induced durable objective responses among patients with metastatic or recurrent head and neck squamous cell carcinoma with HRAS mutations, according to results of a single-arm phase 2 study presented at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.

Be sure to check out Healio Dermatology’s live coverage from the American Society for Dermatologic Surgery annual meeting.

CHICAGO — In an educational session here at the American Society for Dermatologic Surgery annual meeting, Chrysalyne Schmults, MD, of Brigham and Women’s Hospital, provided an update on squamous cell carcinoma, including how to prevent patients from entering the high-risk category and available treatment options.

CHICAGO — For world-renowned chef Grant Achatz, attaining the title of best restaurant in America by Gourmet Magazine was his second greatest challenge compared with fighting the stage IV tongue cancer which nearly cost him his life.

An increase in overall cancer mortality risk was found in patients with severe psoriasis, and associations were identified within site-specific cancers such as colon and kidney among patients with all severities of psoriasis, according to a systematic review of 58 studies that was published in JAMA Dermatology.

BARCELONA — Targeted therapies for non-small cell lung cancer demonstrated potential benefit in additional molecular stratifications of the disease, according to results from the National Lung Matrix Trial presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer.

A nonmelanoma skin cancer risk prediction model using readily available information in the electronic medical records system and a deep learning approach appeared to demonstrate robust discrimination, according to findings published in JAMA Dermatology.

The rates of melanoma, the deadliest form of skin cancer, are increasing exponentially, with research presented at the American Academy of Dermatology Summer Meeting reporting an 800% increase between 1970 and 2009 among women aged 18 to 39 years.