Squamous Cell Carcinoma

Ultrasonography was better than clinical examination alone for detecting regional lymph node metastasis in high-risk cutaneous squamous cell carcinoma of the head and neck, according to a study.

Mohs micrographic surgery showed continued efficacy in preventing local recurrence and progression in high-risk cutaneous squamous cell carcinoma, according to a study.

FDA’s Oncologic Drugs Advisory Committee today voted 13 to 4 to recommend deferral of a regulatory decision on retifanlimab for the treatment of certain patients with squamous cell carcinoma of the anal canal.

Tislelizumab improved overall survival compared with investigator-chosen standard chemotherapy in patients with esophageal squamous cell carcinoma, according to data from a phase 3 study presented at ASCO21.

The addition of nivolumab to chemotherapy or ipilimumab significantly improved OS compared with chemotherapy alone among patients with previously untreated advanced esophageal squamous cell carcinoma, according to phase 3 study findings.

Patients with head and neck cancer experienced an increase in epigenetic age acceleration, especially directly after treatment, which appeared associated with greater fatigue and inflammation, according to a study in Cancer.

Diagnosis with actinic keratosis at age younger than 49 years or older than 80 years was associated with elevated cutaneous squamous cell carcinoma risk, according to a study.

GERD appeared to increase risk for esophageal adenocarcinoma, esophageal squamous cell carcinoma and laryngeal squamous cell carcinoma, according to results of a study published in Cancer.

Patients treated with cemiplimab for advanced cutaneous squamous cell carcinoma had improvements to quality of life, pain and other symptoms, according to a presentation at South Beach Symposium Medical Dermatology Summit.

The FDA granted priority review to retifanlimab for treatment of certain patients with squamous cell carcinoma of the anal canal, according to the agent’s manufacturer.