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Squamous Cell Carcinoma

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November 11, 2023
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Extensive perineural invasion may be optimal prognostic measure for poor CSCC outcomes

Extensive perineural invasion may be optimal prognostic measure for poor CSCC outcomes

Extensive perineural invasion may be the optimal prognostic measure of perineural invasion and poor cutaneous squamous cell carcinoma outcomes, according to a study.

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September 19, 2023
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20-gene expression profile may improve risk stratification in cSCC

20-gene expression profile may improve risk stratification in cSCC

A 20-gene signature prediction demonstrated high accuracy in diagnosing metastasis risk in patients with cutaneous squamous cell carcinoma, according to a study.

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September 07, 2023
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RNA-sequencing, spatial transcriptomics trace ‘aggressive behavior’ in SCC

RNA-sequencing, spatial transcriptomics trace ‘aggressive behavior’ in SCC

Single-cell RNA-sequencing and spatial transcriptomics may be able to identify tumor-specific keratinocyte subpopulations that mark aggressive squamous cell carcinoma in at-risk patients, according to a review.

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July 28, 2023
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High-risk sexual behavior alone may not increase risk for oropharyngeal cancer

High-risk sexual behavior alone may not increase risk for oropharyngeal cancer

High-risk sexual behavior may not be the primary contributor to the development of oropharyngeal squamous cell carcinoma, according to data published in Cancers.

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July 26, 2023
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Organ transplant recipients with cSCC face greater risks for recurrence, metastasis, death

Organ transplant recipients with cSCC face greater risks for recurrence, metastasis, death

Organ transplant recipients diagnosed with cutaneous squamous cell carcinoma are more likely to experience recurrence, metastasis and death from this cancer compared with non-organ transplant recipients, according to a study.

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July 11, 2023
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Personalized oral cancer survival calculator accounts for coexisting conditions

Personalized oral cancer survival calculator accounts for coexisting conditions

A publicly available calculator effectively estimated survival among a cohort of patients with oral squamous cell carcinoma, according to study results published in Otolaryngology-Head and Neck Surgery.

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March 08, 2023
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FDA issues safety communication about cancers in scar tissue around breast implants

FDA issues safety communication about cancers in scar tissue around breast implants

The FDA is aware of 19 cases of squamous cell carcinoma in scar tissue that forms around breast implants, the agency announced today in a safety communication.

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March 07, 2023
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Lack of consensus among Mohs surgeons diagnosing in situ carcinoma

Lack of consensus among Mohs surgeons diagnosing in situ carcinoma

While most Mohs surgeons agree on diagnostic differentiations between actinic keratosis and squamous cell carcinoma in situ, variability exists in the interpretation of in situ carcinoma on histological frozen sections, according to a study.

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February 28, 2023
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Need for consensus in diagnostic practices for actinic keratoses, squamous cell carcinoma

Need for consensus in diagnostic practices for actinic keratoses, squamous cell carcinoma

Due to the lack of clarity in literature, widespread implementation of consensus recommendations for actinic keratoses and cutaneous squamous cell carcinoma is needed, according to a study.

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January 19, 2023
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Deep tumor invasion, perineural invasion associated with poor prognosis in CSCC

Deep tumor invasion, perineural invasion associated with poor prognosis in CSCC

Tumor invasion beyond the subcutaneous fat, along with perineural invasion, were associated with poor outcomes in primary cutaneous squamous cell carcinoma, according to a study.

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