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Squamous Cell

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September 19, 2023
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20-gene expression profile may improve risk stratification in cSCC

A 20-gene signature prediction demonstrated high accuracy in diagnosing metastasis risk in patients with cutaneous squamous cell carcinoma, according to a study.

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September 07, 2023
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RNA-sequencing, spatial transcriptomics trace ‘aggressive behavior’ in SCC

Single-cell RNA-sequencing and spatial transcriptomics may be able to identify tumor-specific keratinocyte subpopulations that mark aggressive squamous cell carcinoma in at-risk patients, according to a review.

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July 26, 2023
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Organ transplant recipients with cSCC face greater risks for recurrence, metastasis, death

Organ transplant recipients diagnosed with cutaneous squamous cell carcinoma are more likely to experience recurrence, metastasis and death from this cancer compared with non-organ transplant recipients, according to a study.

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March 16, 2023
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Top in hem/onc: Safety communication on breast implants; cancer benefits of seaweed sugar

Last week, the FDA issued a safety communication stating that it has identified cases of squamous cell carcinoma in scar tissue that formed around breast implants.

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March 07, 2023
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Lack of consensus among Mohs surgeons diagnosing in situ carcinoma

While most Mohs surgeons agree on diagnostic differentiations between actinic keratosis and squamous cell carcinoma in situ, variability exists in the interpretation of in situ carcinoma on histological frozen sections, according to a study.

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February 28, 2023
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Need for consensus in diagnostic practices for actinic keratoses, squamous cell carcinoma

Due to the lack of clarity in literature, widespread implementation of consensus recommendations for actinic keratoses and cutaneous squamous cell carcinoma is needed, according to a study.

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October 24, 2022
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Nivolumab produces ‘significant clinical activity’ in cutaneous squamous cell carcinoma

More than half of patients had an objective response to first-line nivolumab for locally advanced or metastatic cutaneous squamous cell carcinoma, phase 2 study results published in Cancer showed.

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August 03, 2022
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Atezolizumab plus chemotherapy regimen safe, effective for squamous cell anal carcinoma

Atezolizumab plus a modified docetaxel, cisplatin and 5-fluorouracilregimen is a safe and effective first-line treatment for locally advanced squamous cell anal carcinoma, according to research presented at 2022 ASCO Annual Meeting.