Spontaneous Coronary Artery Dissection

Researchers reported that high concentrations of common genetic variants within families were associated with increased inherited risk for spontaneous coronary artery dissection.

Influenza-like illness was associated with increased risk for arterial dissections in the aorta, the cervical and coronary arteries, according to a study published in Stroke.

Spontaneous coronary artery dissection is a life-altering event that predominantly affects women, but there is little consensus about how to best diagnose and treat it.

In a large cohort of patients with spontaneous coronary artery dissection, the rates of mortality and recurrent spontaneous coronary artery dissection were low at 3 years, researchers reported.

Mortality from CAD has fallen dramatically in the U.S. overall during the past 40 years due to rapid progress in prevention and treatment strategies, yet data show younger women have not benefited from this trend.

Approximately one in five adults with spontaneous coronary artery dissection with high-risk features had an increased burden of rare genetic variants on whole-exome sequencing, suggesting testing may be considered, researchers reported.

More extensive stenting improved coronary perfusion and reduced myocardial injury among high-risk patients with spontaneous coronary artery dissection, but was linked to elevated risk for procedural complications, researchers reported.

Among patients with spontaneous coronary artery dissection, or SCAD, medical therapy was comparable to invasive therapy in long-term risk for death, recurrence and repeat revascularization, researchers reported.