Spleen
Pelabresib reduces spleen volume, symptoms related to myelofibrosis
The combination of pelabresib plus ruxolitinib significantly increased the proportion of patients with myelofibrosis who achieved a clinically meaningful reduction in spleen volume, according to the agent’s manufacturer.
Q&A: BIO89-100 reduces spleen volume, liver fat in NASH
BIO89-100, a long-acting glycopegylated fibroblast growth factor 21 analogue, decreased spleen volume that correlated with reduced liver fat, liver fat volume and PRO-C3 levels among patients with nonalcoholic steatohepatitis, data show.
Researchers identify ‘hidden’ life cycle of malaria parasites in human spleen
Researchers said they have identified a new “hidden” life cycle of malaria parasites in the human spleen — a finding that could have implications for malaria elimination programs, one of them said.
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Gerhardt's Sign
Also known as “Sailer’s sign," in severe aortic valve regurgitation, Gerhardt’s sign is present when pulsations of the spleen are detected in the presence of splenomegaly. This is from the large forward stroke volume that is present in this state.