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Sickle Cell Disease

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June 18, 2021
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Eight important updates for World Sickle Cell Day

Eight important updates for World Sickle Cell Day

World Sickle Cell Day is observed each year on June 19.

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June 11, 2021
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FDA lifts hold on trials of gene therapies for sickle cell disease, beta-thalassemia

The FDA lifted the clinical holds on four studies designed to evaluate two gene therapies for hematologic conditions.

News
May 18, 2021
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Poor lung function linked to fetal death among pregnant women with sickle cell disease

Poor lung function linked to fetal death among pregnant women with sickle cell disease

Pregnant women with sickle cell disease who had poor baseline gestational pulmonary function had significantly greater risk for fetal death, according to study results published in American Journal of Hematology.

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May 17, 2021
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Gene therapy for sickle cell disease shows curative potential

Gene therapy for sickle cell disease shows curative potential

Three patients with sickle cell disease who received the investigational gene therapy ARU-1801 achieved and maintained normal hemoglobin levels, according to early results of a phase 1/phase 2 trial.

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May 03, 2021
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FDA approves Ferriprox for transfusional iron overload due to sickle cell disease

FDA approves Ferriprox for transfusional iron overload due to sickle cell disease

The FDA approved deferiprone for treatment of children or adults with transfusional iron overload due to sickle cell disease or other anemias.

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February 26, 2021
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Transplant increases survival for patients with kidney failure due to sickle cell disease

Transplant increases survival for patients with kidney failure due to sickle cell disease

Patients with sickle cell disease-related kidney failure experienced similar reductions in mortality following transplantation as those whose kidney failure stemmed from other causes, according to researchers from Johns Hopkins.

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February 25, 2021
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Top in hem/onc: Sickle cell gene therapy, primary care in cancer centers

Top in hem/onc: Sickle cell gene therapy, primary care in cancer centers

Last week, bluebird bio suspended clinical trials with its LentiGlobin product for sickle cell disease due to reported cases of hematologic malignancies among patients who received the treatment. It was the top story in hematology/oncology.

News
February 17, 2021
8 min read
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Celebrating Black Pioneers of Medicine

Celebrating Black Pioneers of Medicine

The Association for the Study of African American Life and History instituted an annual celebration and recognition of Black history in 1926.

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February 17, 2021
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Manufacturer suspends clinical trials for gene therapy to treat sickle cell disease

Manufacturer suspends clinical trials for gene therapy to treat sickle cell disease

Gene therapy developer bluebird bio suspended clinical trials using its LentiGlobin product for sickle cell disease due to reported cases of hematologic malignancies among patients who received the treatment.

News
January 07, 2021
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Sickle cell trait not tied to higher risk for MI, CHD in Black individuals

Sickle cell trait not tied to higher risk for MI, CHD in Black individuals

Sickle cell trait was not associated with increased risk for MI or CHD in Black individuals, according to a cohort study published in JAMA Network Open.

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