Sex Hormone-Binding Globulin

Men with lower concentrations of sex hormone-binding globulin may be less likely to sustain a fracture than those with higher levels, according to data published in The Journal of Clinical Endocrinology & Metabolism.

BOSTON — In this video exclusive, Andrea Dunaif, MD, discusses some of the latest research on polycystic ovary syndrome featured at the ENDO 2024.

Low testosterone among men and low sex hormone-binding globulin among women are associated with progression from prediabetes to diabetes, according to a study published in The Journal of Clinical Endocrinology & Metabolism.

Exposure to moderate or high levels of some phthalates is associated with lower levels of sex hormone-binding globulin and a higher risk for obesity among women, according to study data.

SAN DIEGO — Higher sex hormone-binding globulin levels may predict liver fibrosis for men with nonalcoholic fatty liver disease, according to a presenter at the AACE Annual Scientific and Clinical Conference.

Researchers have identified two distinct subtypes of polycystic ovary syndrome associated with novel gene regions, a discovery that could improve disease diagnosis and potentially provide new pathways for drug targets.

Researchers observed a U-shaped relationship between circulating testosterone levels and fracture risk among a cohort of Australian men, with men with a midrange plasma testosterone concentration at lowest risk for sustaining any fracture or hip fracture during a decade of follow-up, according to findings from a community-based study published in The Journal of Clinical Endocrinology & Metabolism.

Sex hormone-binding globulin, or SHBG, may be used as a risk stratification tool to predict ischemic stroke in women based on the inverse association between both factors, according to data presented at the International Stroke Conference.

Women with hyperandrogenemia are at greater risk for metabolic syndrome, dysglycemia than women without hyperandrogenemia, and this heightened risk may be predicted by sex hormone-binding globulin levels, according to findings published in Obesity.

Among men aged at least 70 years, type 2 diabetes appeared associated with a 35% reduction in risk for prostate cancer after consideration of standard risk factors, according to findings published in The Journal of Clinical Endocrinology & Metabolism.