Sepsis
Top in ID: FDA approves adult pneumococcal vaccine; Healio interviews CDC director
The FDA has approved Capvaxive, Merck’s 21-valent pneumococcal vaccine, which is specifically made to protect adults.
AI could help speed antibiotic selection for sepsis
An AI system correctly chose antibiotics for sepsis treatment faster than the standard method using blood cultures, according to a study presented at ASM Microbe.
‘Likely clinically important benefit’ with continuous beta-lactam antibiotic infusions
More ICU patients with sepsis receiving a continuous vs. intermittent infusion of beta-lactam antibiotics achieved clinical cure by day 14, but 90-day mortality was similar, according to research published in JAMA.
Antibiotic stewardship works in NICUs, more evidence shows
Findings from a literature review published in Pediatrics provided more evidence that antimicrobial stewardship reduces antimicrobial use in NICUs without an increase in adverse events.
Greater hospital racial diversity linked to poorer mechanical ventilation outcomes
SAN DIEGO — Patients ventilated for pneumonia or sepsis faced higher mortality odds as the racial diversity of the patient population increased, according to a poster presented at the American Thoracic Society International Conference.
Study: Megalocytic interstitial nephritis may trigger renal transplant rejection
LONG BEACH, Calif. — Megalocytic interstitial nephritis may trigger issues with coexisting renal transplant rejection, and providers should focus on immunosuppressive regimen and infection control, according to presented data.
Acetaminophen lowers acute respiratory distress syndrome development in sepsis
SAN DIEGO — Fewer patients with sepsis receiving acetaminophen vs. placebo developed acute respiratory distress syndrome, according to research presented at the American Thoracic Society International Conference.
High predictability, low false positives with pregnancy-adjusted sepsis screening tools
SAN FRANCISCO — During childbirth hospitalizations, pregnancy-adjusted vs. non-adjusted screening tools had the highest prediction rate and lowest false-positive rates for sepsis, according to results of a case-control study.
Perioperative IV dexamethasone not associated with PJI, wound complications after TSA
According to published results, use of perioperative IV dexamethasone was not associated with increased risk of periprosthetic joint infection or wound healing complications after total shoulder arthroplasty.
Low likelihood of antimicrobials for sepsis during shift changes, night shifts
During hours of the day signaling shift changes and night shifts, the likelihood of starting antimicrobials for hospital-onset sepsis was reduced, according to study results published in Annals of the American Thoracic Society.