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Secukinumab

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September 19, 2024
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Higher secukinumab dose yields no clinical difference after inadequate response in AS

Higher secukinumab dose yields no clinical difference after inadequate response in AS

Increasing the dosage of secukinumab failed to improve ankylosing spondylitis outcomes among patients who initially demonstrated an inadequate treatment response, according to data published in Rheumatology.

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September 04, 2024
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Secukinumab demonstrates efficacy for psoriasis in patients with skin of color

Secukinumab demonstrates efficacy for psoriasis in patients with skin of color

Secukinumab was shown to be safe and efficacious in treating psoriasis in patients with skin of color, according to a study.

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July 26, 2024
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‘On the cusp of a new era’: Promising drugs may tackle unmet needs in giant cell arteritis

‘On the cusp of a new era’: Promising drugs may tackle unmet needs in giant cell arteritis

Nearly all rheumatologists who responded to a recent survey reported patients with giant cell arteritis are in dire need of new treatments, according to a market analysis from Spherix Global Insights.

Clinical Guidance
Ankylosing Spondylitis
Assessment and Treatment

Biologics Targeting Interleukin-17

Muhammad Asim Kahn, MD, FRCP, MACP; Nurullah Akkoç, MD

Free clinical reference tool that includes treatment options; diagnosis information; guidelines; and more.

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May 24, 2024
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IL-17 inhibitors may break TNFi ‘glass ceiling’ in psoriatic arthritis prescribing

IL-17 inhibitors may break TNFi ‘glass ceiling’ in psoriatic arthritis prescribing

Although TNF inhibitors remain the first choice biologic for many rheumatologists treating psoriatic arthritis, interleukin-17 inhibitors may soon overtake them, according to a market analysis from Spherix Global Insights.

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May 20, 2024
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Secukinumab fails to meet proof of concept in lichen planus

Secukinumab fails to meet proof of concept in lichen planus

Secukinumab did not reach proof of concept in patients with lichen planus, according to results of a phase 2 study.

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February 28, 2024
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Low blood monocyte counts in psoriasis patients may predict better response to secukinumab

Low blood monocyte counts in psoriasis patients may predict better response to secukinumab

Patients with plaque psoriasis that have lower baseline blood monocyte counts may respond to secukinumab therapy earlier than patients with higher counts, according to a study.

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December 30, 2023
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Novartis reports sales up 12% in Q3 2023 as ‘pure-play’ transformation complete

Novartis reports sales up 12% in Q3 2023 as ‘pure-play’ transformation complete

Novartis sales grew 12% on a constant currency basis, with core operating income up 21%, in the third quarter of 2023 compared with this time last year, according to a company press release.

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November 20, 2023
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‘This gives us more leeway’: Intravenous secukinumab effective in axial spondyloarthritis

‘This gives us more leeway’: Intravenous secukinumab effective in axial spondyloarthritis

SAN DIEGO — An intravenous formulation of secukinumab met all primary efficacy endpoints, with an attractive safety profile, in patients with axial spondyloarthritis over 52 weeks, according to data presented at ACR Convergence 2023.

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November 01, 2023
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FDA approves Cosentyx as first IL-17A inhibitor for hidradenitis suppurativa

FDA approves Cosentyx as first IL-17A inhibitor for hidradenitis suppurativa

The FDA has approved Cosentyx for the treatment of adults with moderate to severe hidradenitis suppurativa, Novartis announced in a press release.

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