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Schizophrenia

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November 29, 2023
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FDA accepts KarXT new drug application for treating schizophrenia

FDA accepts KarXT new drug application for treating schizophrenia

The FDA has accepted a new drug application from Karuna Therapeutics for KarXT, an investigational muscarinic antipsychotic for the treatment of schizophrenia in adults, the company announced in a press release.

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November 06, 2023
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Brilaroxazine shows promise for schizophrenia in pivotal phase 3 trial

Brilaroxazine shows promise for schizophrenia in pivotal phase 3 trial

Brilaroxazine, a potential new treatment for schizophrenia, significantly improved symptoms and was well-tolerated in a pivotal phase 3 trial, according to a press release from its manufacturer.

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October 25, 2023
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Earlier follow-up lowered suicide risk after psychiatric inpatient discharge

Earlier follow-up lowered suicide risk after psychiatric inpatient discharge

An earlier follow-up visit after psychiatric inpatient discharge was associated with lower risk of suicide in a population-based study from South Korea.

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October 02, 2023
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Karuna Therapeutics submits new drug application to FDA for schizophrenia treatment

Karuna Therapeutics submits new drug application to FDA for schizophrenia treatment

Karuna Therapeutics Inc. has submitted a new drug application to the FDA for KarXT, its investigational muscarinic antipsychotic for the treatment of schizophrenia.

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September 22, 2023
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‘Don’t give up’: Catatonic woman wakes up after 20 years following treatment for lupus

‘Don’t give up’: Catatonic woman wakes up after 20 years following treatment for lupus

A woman diagnosed with schizophrenia and psychosis who was nonverbal and nonresponsive for 2 decades recently “woke” after treatment with pulse steroids and cyclophosphamide.

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September 01, 2023
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Top news of August: Patient-provider relationships, mold and mildew, schizophrenia, more

Top news of August: Patient-provider relationships, mold and mildew, schizophrenia, more

Healio compiled the most-read news in allergy, asthma and immunology posted in August.

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August 17, 2023
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Atopic dermatitis may be associated with schizophrenia, schizoaffective disorder

Atopic dermatitis may be associated with schizophrenia, schizoaffective disorder

Atopic dermatitis was associated with increased odds for schizophrenia and schizoaffective disorder, according to a study published in Archives of Dermatological Research.

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August 16, 2023
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Once-daily schizophrenia treatment falls short of endpoints in two phase 3 trials

Once-daily schizophrenia treatment falls short of endpoints in two phase 3 trials

Two phase 3 studies of a once-daily treatment for schizophrenia failed to meet their primary endpoints, with developers pointing to placebo effects and disruption from the COVID-19 pandemic to possibly explain the drug’s performance.

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July 14, 2023
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AbbVie committed to extending clinical value of its therapeutics

AbbVie committed to extending clinical value of its therapeutics

BOSTON — With a multitude of products spanning neuroscience and psychiatry, executives at AbbVie say they are committed to learning the full clinical value of all of the company’s products for the benefit of patients.

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July 11, 2023
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Symptom dimensions within bipolar disorder may have distinct causes

Symptom dimensions within bipolar disorder may have distinct causes

Symptom dimensions within bipolar disorder may have distinct causes, supporting the hypothesis that genetic heterogeneity underpins clinical heterogeneity, according to a study published in The Lancet Psychiatry.

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