Schizophrenia

Anhedonia severity differed across various disorders, according to results of a systematic review and meta-analysis published in JAMA Network Open.

Aripiprazole lauroxil offered safe and clinically significant symptom improvement for patients with schizophrenia, according to study results published in Journal of Clinical Psychiatry.

A combination of olanzapine and samidorphan was well-tolerated and linked to less weight gain and smaller increases in waist circumference vs. olanzapine alone, according to study results published in American Journal of Psychiatry.

Exposure to stressful life events during adulthood was linked to poorer health, especially among those with high environmental liability for schizophrenia, according to study results published in JAMA Psychiatry.

Long-acting injectable antipsychotic use among patients with early-phase schizophrenia appeared to significantly delay time to hospitalization, according to results of a randomized clinical trial published in JAMA Psychiatry.

Tailored polygenic risk scores appeared to accurately predict progression to bipolar disorder or psychotic disorders, according to study results published in American Journal of Psychiatry.

CV risk in patients with serious mental illness who participate in a program with a health coach compared with controls.

Anxiety level and older age appeared to be associated with rehospitalization among patients with schizophrenia, according to results of a retrospective observational study conducted in Japan and published in Psychiatric Annals.

Several pharmacologic treatments, including vitamin E, may reduce symptoms of tardive dyskinesia, or TD, according to results of a meta-analysis and systematic review published in Journal of Clinical Psychiatry.

An intervention that integrated behavioral counseling, care management and care coordination for patients with serious mental illness significantly reduced overall CV risk, researchers reported.