Sarcopenia

While diabetes is a contributor to the presence of sarcopenic obesity in patients on chronic hemodialysis, it is also a significant predictor of all-cause mortality independent of the presence of obesity, sarcopenia and sarcopenia obesity.

A meta-analysis revealed the presence of sarcopenia increased the risk for death by 143% in patients with nondialysis-dependent chronic renal disease.

Older adults without obesity, but with a high body fat percentage, have greater risks for sarcopenia and osteoporosis when compared with individuals with obesity, according to findings published in Obesity.

Neoadjuvant therapy-induced sarcopenia in patients who underwent neoadjuvant therapy for pancreatic ductal adenocarcinoma correlated with increased disease recurrence and overall mortality, and reduced overall survival, according to a presentation from Digestive Disease Week.

Older men with sarcopenia are more likely to develop type 2 diabetes during 15 years of follow-up compared with men who have more lean body mass, according to findings published in the Journal of the Endocrine Society.

Adults with radioactive iodine-refractory thyroid cancer and sarcopenia who are treated with sorafenib are no more likely to experience a dose modification due to drug toxicity than a similar patient without sarcopenia, according to findings from an exploratory analysis of the DECISION trial.

Prolonged use of menopausal hormone therapy is associated with high skeletal muscle mass and a low prevalence of sarcopenia among postmenopausal women, according to findings published in Menopause.

Among adults with type 2 diabetes, estimated glomerular filtration rate may fall to a greater degree if a patient also has sarcopenia and obesity, according to findings published in Diabetic Medicine.

Frailty correlated with a twofold higher risk for waitlist mortality among both patients with and without obesity in need of liver transplantation, which increased to a threefold higher risk in those with class 2 or higher obesity, according to a study published in JAMA Surgery.

High serum sclerostin levels are independently correlated with low muscle mass in healthy Korean adults, according to findings published in Bone.