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Roswell Park Comprehensive Cancer Center

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October 10, 2019
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HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma

Phase 1 study to determine the safety and feasibility of using HERV-E TCR-transduced autologous T Cells in patients with metastatic clear-cell renal-cell carcinoma.

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October 10, 2019
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HA-1 T TCR T Cell Immunotherapy for the Treating of Patients with Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Phase 1 study of adoptive immunotherapy with CD8+ and CD4+ memory T cells transduced to express an HA-1-specific T cell receptor for children and adults with recurrent acute leukemia after allogeneic hematopoietic stem cell transplantation.

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October 10, 2019
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Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

Phase 1 dose-escalation clinical trial to determine the phase 2 dose of autologous TIL 1383I TCR gene-modified T cells using a retrovirus for patients with advanced melanoma.

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July 30, 2019
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Ovarian Cancer Research Alliance honors Roswell Park deputy director

Ovarian Cancer Research Alliance honors Roswell Park deputy director

Ovarian Cancer Research Alliance presented its Rosalind Franklin Prize for Excellence in Ovarian Cancer Research to Kunle Odunsi, MD, PhD, FRCOG, FACOG.

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June 17, 2019
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MIW815 plus spartalizumab safe, active among certain patients with advanced breast cancer, melanoma

CHICAGO — Patients with anti-PD-1-naive triple-negative breast cancer and PD-1-relapsed or refractory melanoma demonstrated antitumor benefit from MIW815 plus spartalizumab, according to results of a phase 1b study presented at ASCO Annual Meeting.

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April 01, 2019
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Oral contraceptive birth control reduces risk for aggressive ovarian cancer

Oral contraceptive birth control reduces risk for aggressive ovarian cancer

ATLANTA — Oral contraceptive use appeared associated with a reduced risk for highly fatal aggressive ovarian cancer, with a greater risk reduction observed with longer birth control use, according to study results presented at American Association for Cancer Research Annual Meeting.

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March 03, 2019
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Opioid-sparing policy reduces use without increasing pain after surgery

Opioid-sparing policy reduces use without increasing pain after surgery

A restrictive protocol safely and effectively reduced the number of opioids prescribed to patients who underwent gynecologic or abdominal surgery, according to findings from a 2-year pilot case-control study.

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February 08, 2019
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Minimally invasive cervical cancer surgery may promote disease recurrence; professionals urge patience

Minimally invasive cervical cancer surgery may promote disease recurrence; professionals urge patience

Minimally invasive surgeries have emerged as often-preferable alternatives to open surgeries for a variety of malignancies, due to the lower risk for complications and faster time to recovery.

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January 18, 2019
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CIMAvax-nivolumab combination appears safe, demonstrates ‘good signals’ in advanced lung cancer

CIMAvax-nivolumab combination appears safe, demonstrates ‘good signals’ in advanced lung cancer

The Cuban-developed immunotherapy CIMAvax-EGF in combination with nivolumab appeared safe for patients with advanced non-small cell lung cancer, according to results from the first portion of a phase 1/phase 2 trial.

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January 11, 2019
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Roswell Park immunotherapy expert honored for melanoma research

Igor Puzanov, MD, MSCI, FACP, received the Melanoma Foundation Award for outstanding and lifelong contributions to melanoma research.

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