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Respiratory Failure

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June 05, 2025
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Ganciclovir prophylaxis shows no respiratory support-free day, mortality benefit in sepsis

SAN FRANCISCO — Receiving ganciclovir prophylaxis did not have a benefit on respiratory support-free days vs. placebo in adults with sepsis-associated respiratory failure and cytomegalovirus-seropositivity, according to phase 3 trial data.

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May 20, 2025
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Frailty, age, cognition impact odds for post-intensive care syndrome in ICU survivors

SAN FRANCISCO — Greater frailty, older age and worse cognition heightened the odds for a post-intensive care syndrome recovery trajectory in ICU survivors, according to data shared at the American Thoracic Society International Conference.

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December 12, 2024
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High-flow nasal oxygen noninferior to noninvasive ventilation in acute respiratory failure

When assessing intubation/death at 7 days in hospitalized adults with acute respiratory failure, high-flow nasal oxygen was generally noninferior to noninvasive ventilation, according to results published in JAMA.

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October 08, 2024
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Cannabis use lowers odds for mortality, respiratory failure in COVID-19 hospitalization

BOSTON — During COVID-19 hospitalization, patients faced lower odds for mortality and respiratory failure with vs. without documented cannabis use, according to data presented at the CHEST Annual Meeting.

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October 07, 2024
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ROX index in acute hypoxic respiratory failure predicts high-flow nasal cannula outcomes

BOSTON — When capturing ROX index in acute hypoxic respiratory failure, time from the start of high-flow nasal cannula therapy impacted the index’s sensitivity and specificity, according to data presented at the CHEST Annual Meeting.

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October 06, 2024
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Metabolically healthy obesity heightens respiratory, cardiac complication odds in COPD

BOSTON — Older adults hospitalized for an acute COPD exacerbation with vs. without metabolically healthy obesity were more likely to experience respiratory and cardiac complications, according to data presented at the CHEST Annual Meeting.

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August 28, 2024
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Antifibrotics increase survival probability in COVID-19, acute respiratory failure

Among patients with COVID-19 and acute respiratory failure, survival at 1 year was more likely if they received nintedanib or pirfenidone antifibrotics, according to results published in BMC Pulmonary Medicine.

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June 06, 2024
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Amid suffering, a lesson learned: ‘We can always find space to hope’

Editor’s note: This is the first in a series of five stories from ASCO Voices, a session during the 2024 ASCO Annual Meeting focused on the human side of oncology.

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April 08, 2024
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Chest radiograph interpretation sparks disagreement over pediatric ARDS diagnosis

Use of the 2015 Pediatric Acute Lung Injury Consensus Conference, or PALICC, criteria for diagnosing pediatric acute respiratory distress syndrome mostly resulted in agreement between two physicians, according to results published in CHEST.

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March 15, 2024
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Virtual reality-based training helps pediatric nurses identify respiratory distress

Among new nurses, receipt of virtual reality-based training vs. usual orientation led to more correct identification of respiratory distress in pediatric patients, according to results published in American Journal of Critical Care.

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